Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 1312686..1313933 | Replicon | chromosome |
| Accession | NC_008391 | ||
| Organism | Burkholderia ambifaria AMMD | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | Q0B7E4 |
| Locus tag | BAMB_RS21910 | Protein ID | WP_011659358.1 |
| Coordinates | 1313352..1313933 (+) | Length | 194 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | BAMB_RS21905 | Protein ID | WP_011659357.1 |
| Coordinates | 1312686..1313243 (+) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BAMB_RS21885 | 1308584..1309219 | + | 636 | WP_011659353.1 | cysteine hydrolase | - |
| BAMB_RS21890 | 1309288..1310019 | - | 732 | WP_011659354.1 | ribonuclease T2 | - |
| BAMB_RS21895 | 1310201..1311604 | - | 1404 | WP_011659355.1 | hypothetical protein | - |
| BAMB_RS21900 | 1311967..1312614 | + | 648 | WP_011659356.1 | hypothetical protein | - |
| BAMB_RS21905 | 1312686..1313243 | + | 558 | WP_011659357.1 | helix-turn-helix domain-containing protein | Antitoxin |
| BAMB_RS21910 | 1313352..1313933 | + | 582 | WP_011659358.1 | HD domain-containing protein | Toxin |
| BAMB_RS21915 | 1314013..1315551 | - | 1539 | WP_011659359.1 | MFS transporter | - |
| BAMB_RS21920 | 1315729..1316634 | + | 906 | WP_011659360.1 | LysR family transcriptional regulator | - |
| BAMB_RS21925 | 1316696..1317835 | - | 1140 | WP_011659361.1 | enoyl-CoA hydratase/isomerase family protein | - |
| BAMB_RS21930 | 1317832..1318623 | - | 792 | WP_011659362.1 | enoyl-CoA hydratase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 194 a.a. Molecular weight: 21455.98 Da Isoelectric Point: 4.8564
>T21712 WP_011659358.1 NC_008391:1313352-1313933 [Burkholderia ambifaria AMMD]
MNLDTIHARLDFLREAERLKDVLRSGHTSTGRRESTAEHSWRLCLMALVFADALPDVDTTKLLKLCVVHDLGEALHGDIP
AIEQAAHPDKSTHERDDLLTLTAGLDRALRDEIVALWDEYEAAESPEARAAKALDKLETILQHNQGSNPPDFDYAFNLGY
GRRYTDATPLFGAIRAIVDADTQRRIDARGDGA
MNLDTIHARLDFLREAERLKDVLRSGHTSTGRRESTAEHSWRLCLMALVFADALPDVDTTKLLKLCVVHDLGEALHGDIP
AIEQAAHPDKSTHERDDLLTLTAGLDRALRDEIVALWDEYEAAESPEARAAKALDKLETILQHNQGSNPPDFDYAFNLGY
GRRYTDATPLFGAIRAIVDADTQRRIDARGDGA
Download Length: 582 bp
>T21712 NC_008391:1313352-1313933 [Burkholderia ambifaria AMMD]
ATGAACCTCGACACGATCCACGCGCGGCTCGATTTCCTGCGCGAAGCCGAACGCCTGAAAGACGTGCTGCGCAGCGGCCA
CACGTCGACGGGCCGCCGCGAAAGCACGGCGGAGCACAGCTGGCGACTGTGCCTGATGGCGCTCGTGTTCGCCGATGCGC
TGCCCGACGTCGACACGACGAAGCTGCTGAAACTGTGCGTCGTCCACGATCTCGGCGAAGCGCTGCACGGCGACATCCCC
GCGATCGAGCAGGCCGCGCATCCGGACAAGAGCACGCATGAACGCGACGACCTGCTGACGCTCACGGCCGGGCTCGATCG
CGCGCTGCGCGACGAGATCGTCGCGCTGTGGGACGAATACGAGGCGGCCGAATCACCGGAAGCGCGCGCCGCGAAGGCGC
TCGACAAGCTCGAGACGATTCTGCAGCACAACCAGGGCAGCAATCCGCCCGACTTCGACTACGCGTTCAATCTCGGCTAC
GGGCGGCGCTACACCGACGCGACGCCGCTGTTCGGCGCGATCCGCGCGATCGTCGACGCGGACACACAACGCAGGATCGA
CGCACGCGGCGACGGCGCGTAA
ATGAACCTCGACACGATCCACGCGCGGCTCGATTTCCTGCGCGAAGCCGAACGCCTGAAAGACGTGCTGCGCAGCGGCCA
CACGTCGACGGGCCGCCGCGAAAGCACGGCGGAGCACAGCTGGCGACTGTGCCTGATGGCGCTCGTGTTCGCCGATGCGC
TGCCCGACGTCGACACGACGAAGCTGCTGAAACTGTGCGTCGTCCACGATCTCGGCGAAGCGCTGCACGGCGACATCCCC
GCGATCGAGCAGGCCGCGCATCCGGACAAGAGCACGCATGAACGCGACGACCTGCTGACGCTCACGGCCGGGCTCGATCG
CGCGCTGCGCGACGAGATCGTCGCGCTGTGGGACGAATACGAGGCGGCCGAATCACCGGAAGCGCGCGCCGCGAAGGCGC
TCGACAAGCTCGAGACGATTCTGCAGCACAACCAGGGCAGCAATCCGCCCGACTTCGACTACGCGTTCAATCTCGGCTAC
GGGCGGCGCTACACCGACGCGACGCCGCTGTTCGGCGCGATCCGCGCGATCGTCGACGCGGACACACAACGCAGGATCGA
CGCACGCGGCGACGGCGCGTAA
Antitoxin
Download Length: 186 a.a. Molecular weight: 20252.28 Da Isoelectric Point: 11.0874
>AT21712 WP_011659357.1 NC_008391:1312686-1313243 [Burkholderia ambifaria AMMD]
MTTSPLHTPPLGPQLKRWRTLRRVKQSHAAELFGVAQSTISRWEAGIQQMSPDERATAERLLAARLDSAGDHALARLIAS
STARMHLVCDLTHRLLACAPSRAAEFSRPLPALLGTSLWRYASPEIVRMEAALDPLGWHDRAGPPSVEFATGINASRVVP
IRGSTCRWTRMTLSDGSAARLVETL
MTTSPLHTPPLGPQLKRWRTLRRVKQSHAAELFGVAQSTISRWEAGIQQMSPDERATAERLLAARLDSAGDHALARLIAS
STARMHLVCDLTHRLLACAPSRAAEFSRPLPALLGTSLWRYASPEIVRMEAALDPLGWHDRAGPPSVEFATGINASRVVP
IRGSTCRWTRMTLSDGSAARLVETL
Download Length: 558 bp
>AT21712 NC_008391:1312686-1313243 [Burkholderia ambifaria AMMD]
ATGACGACCTCGCCGCTTCACACCCCGCCGCTCGGCCCGCAACTCAAGCGCTGGCGCACGCTGCGCCGCGTGAAGCAGAG
CCATGCAGCCGAGCTGTTCGGCGTCGCGCAATCGACAATCTCGCGCTGGGAAGCCGGCATCCAGCAGATGTCGCCCGACG
AGCGCGCAACGGCCGAGCGGCTGCTTGCCGCGCGTCTCGATTCGGCCGGCGACCACGCGCTCGCGCGGCTGATCGCGAGC
AGCACGGCCCGCATGCATCTCGTGTGCGACCTCACGCATCGCTTGCTCGCCTGCGCGCCGTCGCGCGCGGCAGAGTTCTC
GCGGCCGCTGCCGGCCTTGCTCGGTACCTCGCTGTGGCGCTATGCGTCGCCGGAAATCGTGCGCATGGAAGCCGCGCTCG
ACCCGCTCGGCTGGCACGATCGCGCGGGGCCGCCGAGCGTCGAATTCGCGACCGGCATCAATGCGTCGCGCGTCGTGCCG
ATCCGCGGCAGCACCTGCCGGTGGACGCGCATGACGCTGTCGGACGGCTCCGCCGCGCGGCTCGTCGAAACGCTGTAG
ATGACGACCTCGCCGCTTCACACCCCGCCGCTCGGCCCGCAACTCAAGCGCTGGCGCACGCTGCGCCGCGTGAAGCAGAG
CCATGCAGCCGAGCTGTTCGGCGTCGCGCAATCGACAATCTCGCGCTGGGAAGCCGGCATCCAGCAGATGTCGCCCGACG
AGCGCGCAACGGCCGAGCGGCTGCTTGCCGCGCGTCTCGATTCGGCCGGCGACCACGCGCTCGCGCGGCTGATCGCGAGC
AGCACGGCCCGCATGCATCTCGTGTGCGACCTCACGCATCGCTTGCTCGCCTGCGCGCCGTCGCGCGCGGCAGAGTTCTC
GCGGCCGCTGCCGGCCTTGCTCGGTACCTCGCTGTGGCGCTATGCGTCGCCGGAAATCGTGCGCATGGAAGCCGCGCTCG
ACCCGCTCGGCTGGCACGATCGCGCGGGGCCGCCGAGCGTCGAATTCGCGACCGGCATCAATGCGTCGCGCGTCGTGCCG
ATCCGCGGCAGCACCTGCCGGTGGACGCGCATGACGCTGTCGGACGGCTCCGCCGCGCGGCTCGTCGAAACGCTGTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|