Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
| Location | 995295..995842 | Replicon | chromosome |
| Accession | NZ_CP083690 | ||
| Organism | Serratia sp. HRI | ||
Toxin (Protein)
| Gene name | ccdB | Uniprot ID | - |
| Locus tag | GF111_RS04810 | Protein ID | WP_047728145.1 |
| Coordinates | 995295..995603 (-) | Length | 103 a.a. |
Antitoxin (Protein)
| Gene name | ccdA | Uniprot ID | A0A0G3SUU9 |
| Locus tag | GF111_RS04815 | Protein ID | WP_033633717.1 |
| Coordinates | 995606..995842 (-) | Length | 79 a.a. |
Genomic Context
Location: 992326..993246 (921 bp)
Type: Others
Protein ID: WP_038880964.1
Type: Others
Protein ID: WP_038880964.1
Location: 993277..994401 (1125 bp)
Type: Others
Protein ID: WP_038880962.1
Type: Others
Protein ID: WP_038880962.1
Location: 994416..995258 (843 bp)
Type: Others
Protein ID: WP_047728144.1
Type: Others
Protein ID: WP_047728144.1
Location: 991063..992220 (1158 bp)
Type: Others
Protein ID: WP_047728141.1
Type: Others
Protein ID: WP_047728141.1
Location: 995295..995603 (309 bp)
Type: Toxin
Protein ID: WP_047728145.1
Type: Toxin
Protein ID: WP_047728145.1
Location: 995606..995842 (237 bp)
Type: Antitoxin
Protein ID: WP_033633717.1
Type: Antitoxin
Protein ID: WP_033633717.1
Location: 995930..996838 (909 bp)
Type: Others
Protein ID: WP_171887866.1
Type: Others
Protein ID: WP_171887866.1
Location: 996848..997768 (921 bp)
Type: Others
Protein ID: WP_038880960.1
Type: Others
Protein ID: WP_038880960.1
Location: 997821..999356 (1536 bp)
Type: Others
Protein ID: WP_055312408.1
Type: Others
Protein ID: WP_055312408.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GF111_RS04790 (GF111_04790) | 991063..992220 | - | 1158 | WP_047728141.1 | YbfB/YjiJ family MFS transporter | - |
| GF111_RS04795 (GF111_04795) | 992326..993246 | + | 921 | WP_038880964.1 | LysR family transcriptional regulator | - |
| GF111_RS04800 (GF111_04800) | 993277..994401 | + | 1125 | WP_038880962.1 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase | - |
| GF111_RS04805 (GF111_04805) | 994416..995258 | + | 843 | WP_047728144.1 | S-formylglutathione hydrolase | - |
| GF111_RS04810 (GF111_04810) | 995295..995603 | - | 309 | WP_047728145.1 | CcdB family protein | Toxin |
| GF111_RS04815 (GF111_04815) | 995606..995842 | - | 237 | WP_033633717.1 | type II toxin-antitoxin system CcdA family antitoxin | Antitoxin |
| GF111_RS04820 (GF111_04820) | 995930..996838 | - | 909 | WP_171887866.1 | glutathione ABC transporter permease GsiD | - |
| GF111_RS04825 (GF111_04825) | 996848..997768 | - | 921 | WP_038880960.1 | glutathione ABC transporter permease GsiC | - |
| GF111_RS04830 (GF111_04830) | 997821..999356 | - | 1536 | WP_055312408.1 | glutathione ABC transporter substrate-binding protein GsiB | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 a.a. Molecular weight: 11472.26 Da Isoelectric Point: 5.0196
>T217077 WP_047728145.1 NZ_CP083690:c995603-995295 [Serratia sp. HRI]
MQFTVYDNTYPASAYPYLLDVQSDLIDVLSTRLVIPLYALDNVRVKISARLCPEIEVNGEKFLVMTHEMAAVRISQIGKA
VGNVNEHRNQIKAAIDFLIDGF
MQFTVYDNTYPASAYPYLLDVQSDLIDVLSTRLVIPLYALDNVRVKISARLCPEIEVNGEKFLVMTHEMAAVRISQIGKA
VGNVNEHRNQIKAAIDFLIDGF
Download Length: 309 bp
>T217077 NZ_CP113792:54817-55122 [Klebsiella variicola subsp. tropica]
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGCCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGACGGATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAGGTTTCCCGTGAACTCTATCCGGTGG
TGCACATCGGGGACGAAAGCTACCGCCTGATGACCACGGACATGGCCAGCGTCACTTCCTCCGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGCCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGACGGATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAGGTTTCCCGTGAACTCTATCCGGTGG
TGCACATCGGGGACGAAAGCTACCGCCTGATGACCACGGACATGGCCAGCGTCACTTCCTCCGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA
Antitoxin
Download Length: 79 a.a. Molecular weight: 8994.07 Da Isoelectric Point: 5.0807
>AT217077 WP_033633717.1 NZ_CP083690:c995842-995606 [Serratia sp. HRI]
MANNNVTKKTVNVTIDRDLFQRAKSLGVNVSSVLTDALSVRVRDIEIQQWREQNRAALEELNRITEENGLLSDEYRTF
MANNNVTKKTVNVTIDRDLFQRAKSLGVNVSSVLTDALSVRVRDIEIQQWREQNRAALEELNRITEENGLLSDEYRTF
Download Length: 237 bp
>AT217077 NZ_CP113792:54597-54815 [Klebsiella variicola subsp. tropica]
ATGAAGCAGCGCATCACTGTCACCATAGACAGCGACAGTTATCAGTTACTGAAATCCGCAGACGTCAATATCTCCGCCCT
GGTGAACAGGGCCATGCAGAATGAGGCCCGTCGTCTGCGTTCCGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCCG
AGGTTGCCCGATTTATTGAGATGAACGGTTCATTCGCCGACGAAAACAGGGACTGGTGA
ATGAAGCAGCGCATCACTGTCACCATAGACAGCGACAGTTATCAGTTACTGAAATCCGCAGACGTCAATATCTCCGCCCT
GGTGAACAGGGCCATGCAGAATGAGGCCCGTCGTCTGCGTTCCGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCCG
AGGTTGCCCGATTTATTGAGATGAACGGTTCATTCGCCGACGAAAACAGGGACTGGTGA
Structures
Toxin
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Source | ID | Structure |
|---|---|---|
| No matching records found | ||
Antitoxin
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Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0G3SUU9 |