Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_26
Location 668351..668953 Replicon chromosome
Accession NC_008380
Organism Rhizobium leguminosarum bv. viciae 3841

Toxin (Protein)


Gene name relE Uniprot ID A0A154IHS8
Locus tag RL_RS03260 Protein ID WP_011650400.1
Coordinates 668351..668596 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q1MLN9
Locus tag RL_RS03265 Protein ID WP_011650401.1
Coordinates 668606..668953 (+) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RL_RS03220 663839..664270 + 432 WP_003545314.1 DUF2948 family protein -
RL_RS03225 664326..665624 + 1299 WP_011650396.1 histidinol dehydrogenase -
RL_RS03230 665629..666102 + 474 WP_011650397.1 UPF0262 family protein -
RL_RS03235 666099..666584 + 486 WP_011650398.1 low molecular weight phosphatase family protein -
RL_RS03240 666708..666926 + 219 WP_003545338.1 translation initiation factor IF-1 -
RL_RS03245 666985..667605 + 621 WP_003545339.1 Maf-like protein -
RL_RS03250 667735..667947 + 213 WP_011650399.1 DNA gyrase inhibitor YacG -
RL_RS03260 668351..668596 + 246 WP_011650400.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
RL_RS03265 668606..668953 + 348 WP_011650401.1 helix-turn-helix transcriptional regulator Antitoxin
RL_RS03270 669116..669394 - 279 WP_028740383.1 transposase -
RL_RS03275 669402..670862 - 1461 WP_011650403.1 HlyD family type I secretion periplasmic adaptor subunit -
RL_RS03280 670877..672592 - 1716 WP_011650404.1 type I secretion system permease/ATPase -
RL_RS03285 672683..673258 - 576 WP_011650405.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(63-113)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9050.61 Da        Isoelectric Point: 10.7504

>T21702 WP_011650400.1 NC_008380:668351-668596 [Rhizobium leguminosarum bv. viciae 3841]
MKKIAYSKAATKALRKMQPKRAAAIVARVEAFANGESVDLKKLQGSEFFRIRVGQDRVIIDDQTMQVLVIKAGPRGDIYN
E

Download         Length: 246 bp

>T21702 NC_008380:668351-668596 [Rhizobium leguminosarum bv. viciae 3841]
ATGAAAAAGATCGCCTACAGCAAGGCCGCCACGAAGGCACTCCGCAAAATGCAGCCGAAGCGCGCCGCGGCGATCGTCGC
CAGGGTCGAAGCCTTCGCCAACGGTGAGTCAGTCGACCTCAAGAAGCTGCAAGGCAGCGAATTTTTTCGAATTCGTGTCG
GGCAGGACCGTGTCATCATCGACGATCAGACCATGCAGGTCCTCGTCATCAAGGCCGGCCCACGTGGCGACATCTATAAC
GAATAG

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12504.08 Da        Isoelectric Point: 4.3175

>AT21702 WP_011650401.1 NC_008380:668606-668953 [Rhizobium leguminosarum bv. viciae 3841]
MGEIQKLTIDGKGYVLLSEDDYQDLVDISEARAAKARIGAGEETWPEDVVKALIAGEDPVRVFRKHRGMSIKELAEKSGL
SQPYLSEIETGKKEGSLDALRSIASALDVDLDDVA

Download         Length: 348 bp

>AT21702 NC_008380:668606-668953 [Rhizobium leguminosarum bv. viciae 3841]
ATGGGTGAAATCCAGAAACTGACCATCGACGGCAAGGGGTACGTGCTGCTTTCCGAAGACGACTATCAGGACCTTGTCGA
CATCAGCGAGGCGCGTGCCGCAAAGGCGCGTATCGGCGCTGGCGAAGAGACCTGGCCTGAAGACGTCGTCAAGGCGCTGA
TTGCCGGCGAAGATCCTGTCCGGGTGTTCCGTAAGCATCGCGGTATGAGCATCAAGGAGCTGGCTGAAAAGTCCGGGCTC
TCCCAGCCCTATCTTTCGGAAATCGAGACCGGAAAGAAGGAGGGCTCCCTGGACGCACTTAGGTCGATCGCCAGCGCGCT
GGACGTCGATCTTGACGATGTGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A154IHS8

Antitoxin

Source ID Structure
AlphaFold DB Q1MLN9

References