Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 308281..308797 Replicon chromosome
Accession NZ_CP083641
Organism Enterobacter bugandensis strain FDAARGOS_1497

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LA318_RS01495 Protein ID WP_088204684.1
Coordinates 308513..308797 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8E1RL94
Locus tag LA318_RS01490 Protein ID WP_023331889.1
Coordinates 308281..308523 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LA318_RS01475 (LA318_01475) 304371..305111 + 741 WP_041911457.1 KDGP aldolase family protein -
LA318_RS01480 (LA318_01480) 305137..306273 + 1137 WP_088204685.1 lactonase family protein -
LA318_RS01485 (LA318_01485) 306293..308203 + 1911 WP_048999489.1 PRD domain-containing protein -
LA318_RS01490 (LA318_01490) 308281..308523 + 243 WP_023331889.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LA318_RS01495 (LA318_01495) 308513..308797 + 285 WP_088204684.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LA318_RS01500 (LA318_01500) 308801..309265 - 465 WP_088204683.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
LA318_RS01505 (LA318_01505) 309351..311489 - 2139 WP_048960133.1 anaerobic ribonucleoside-triphosphate reductase -
LA318_RS01510 (LA318_01510) 311859..312431 - 573 WP_088204682.1 fructose PTS transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10991.91 Da        Isoelectric Point: 10.0526

>T216990 WP_088204684.1 NZ_CP083641:308513-308797 [Enterobacter bugandensis]
MIYELEFDPRALKEWHKLGDTVKCQFKKKLADVLVNPRIESARLHGLSDCYKIKLRSLGYRLVYQVQDNVVTVFVIAIGK
REKSAVYHEANKRL

Download         Length: 285 bp

>T216990 NZ_CP113538:868330-868743 [Salmonella enterica]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTGATTTTATTGATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGCTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCGTCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CAGGCCAACACTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9030.41 Da        Isoelectric Point: 4.7719

>AT216990 WP_023331889.1 NZ_CP083641:308281-308523 [Enterobacter bugandensis]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTISDSEDELIQTVRERLANPQKGIKVSLDDL

Download         Length: 243 bp

>AT216990 NZ_CP113538:868083-868349 [Salmonella enterica]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGATGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References