Detailed information of TA system TA021692

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /GNAT-DUF1778
• Location: 4723737..4724503
• Replicon: chromosome
• Accession: NC_008345
• Organism: Shewanella frigidimarina NCIMB 400

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: SFRI_RS20350
• Protein ID: WP_041413257.1
• Coordinates: 4724006..4724503 (+)
• Length: 166 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: Q07W31
• Locus tag: SFRI_RS20345
• Protein ID: WP_011639367.1
• Coordinates: 4723737..4724009 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SFRI_RS20330	4719406..4720638	+	1233	WP_011639364.1	imidazolonepropionase	-
SFRI_RS20335	4721000..4721740	+	741	WP_208855610.1	haloacid dehalogenase type II	-
SFRI_RS20340	4721921..4723582	+	1662	WP_011639366.1	amidohydrolase	-
SFRI_RS20345	4723737..4724009	+	273	WP_011639367.1	DUF1778 domain-containing protein	Antitoxin
SFRI_RS20350	4724006..4724503	+	498	WP_041413257.1	GNAT family N-acetyltransferase	Toxin
SFRI_RS20365	4725978..4726481	-	504	WP_011639369.1	hypothetical protein	-
SFRI_RS20375	4726988..4727227	-	240	WP_011639370.1	YdcH family protein	-
SFRI_RS20380	4727409..4729274	+	1866	WP_011639371.1	DUF885 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (86-151)

Antitoxin

• Vibrio phage ICP1, Orf50 (2-89)

Sequences

Toxin

Protein

• Length: 166 a.a.
• Molecular weight: 18549.16 Da
• Isoelectric Point: 7.3542

>T21692 WP_041413257.1 NC_008345:4724006-4724503 [Shewanella frigidimarina NCIMB 400]
IMNTVLLDKAKHDRNRFNCGIEALNNYLKIMASQQAKKDNSRTFILEDDNDNSHIIGFYTLTMTPIDLKALPDKLQKKYQ
SSTSGGLIARLAIDDRYKGQGFGEWLLIDALRKLLAASDSVAFPVVIVDAKDGATHFYEHYGFKAFQDAENKLFITIADV
RTSLS

Nucleotide

• Length: 498 bp

>T21692 NC_008345:4724006-4724503 [Shewanella frigidimarina NCIMB 400]
ATAATGAATACGGTACTTTTAGATAAAGCTAAACACGATAGAAACCGATTCAACTGTGGTATTGAAGCTCTTAATAATTA
CTTAAAAATCATGGCGAGTCAGCAAGCGAAGAAAGACAACAGCAGAACTTTCATTTTAGAAGATGATAACGATAACTCGC
ATATCATTGGCTTTTATACCTTAACAATGACACCAATTGACCTAAAGGCTCTGCCGGATAAGCTACAGAAAAAGTACCAG
TCATCAACGTCTGGCGGCCTTATAGCCCGCTTAGCAATCGATGACCGCTATAAAGGCCAAGGCTTTGGCGAATGGTTACT
TATTGATGCACTACGAAAACTGTTAGCGGCAAGTGATAGCGTAGCATTCCCAGTCGTCATTGTTGACGCAAAAGATGGCG
CGACACACTTCTACGAACACTATGGATTTAAAGCCTTTCAAGACGCAGAAAACAAACTGTTCATCACCATTGCAGATGTA
AGAACAAGCTTAAGTTAA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 9767.26 Da
• Isoelectric Point: 6.2988

>AT21692 WP_011639367.1 NC_008345:4723737-4724009 [Shewanella frigidimarina NCIMB 400]
MATTLPRITARVDVDTQDLLTKAAAIAGMSSINSFVLSAAIEKAKQIIEREQVLKLSQTDAMLLMEALDSPATPNSKLKT
ASERYESKTQ

Nucleotide

• Length: 273 bp

>AT21692 NC_008345:4723737-4724009 [Shewanella frigidimarina NCIMB 400]
ATGGCAACTACTTTACCTCGCATCACCGCTAGAGTTGATGTCGACACCCAAGATTTACTGACAAAGGCAGCAGCAATCGC
TGGTATGTCGAGTATTAATTCATTTGTGCTAAGTGCCGCAATCGAAAAAGCCAAACAAATCATTGAGCGTGAACAAGTAC
TAAAACTAAGTCAAACAGATGCGATGTTGCTTATGGAAGCACTAGACAGTCCAGCAACACCAAACTCAAAACTCAAAACG
GCTTCGGAACGTTACGAAAGCAAAACCCAATAA

Structures

Antitoxin

• AlphaFold DB: A0A3G8LNV6