Detailed information of TA system TA216917

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 1077285..1078024
• Replicon: chromosome
• Accession: NZ_CP083630
• Organism: Leclercia adecarboxylata strain FDAARGOS_1505

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: LA332_RS05210
• Protein ID: WP_058675171.1
• Coordinates: 1077539..1078024 (+)
• Length: 162 a.a.

Antitoxin (Protein)

• Gene name: tacA
• Uniprot ID: A0A085GLQ4
• Locus tag: LA332_RS05205
• Protein ID: WP_032611697.1
• Coordinates: 1077285..1077551 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (27-149)

Antitoxin

• Vibrio phage ICP1, Orf50 (2-87)

Sequences

Toxin

Protein

• Length: 162 a.a.
• Molecular weight: 17692.47 Da
• Isoelectric Point: 9.8719

>T216917 WP_058675171.1 NZ_CP083630:1077539-1078024 [Leclercia adecarboxylata]
VGHVTAPEPLSAFHQVAEFVSGETVLDDWLKQKGLKNQALGAARTFVVCKKDTKQIAGFYSLATGSVNHTEATGNLRRNM
PDPIPVIILARLAVDLSLRGKGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFYIHHGFKPSQTQPRTLFLRLP
Q

Nucleotide

• Length: 486 bp

>T216917 NZ_CP113517:c2316688-2316434 [Methylomonas rapida]
ATGAAACGCAAACACCAAAAAACCATCGAGGCGCTTTTCGCGCATCCTGTCGGCGCGAATATCCCATGGCGCGACATCGA
GTCGCTGTTTCTGGAGCTGGGCGCAACGGTCAGTGAACGCGAAGGTTCACGGGTTTGCGTGGTATTGTTTGGCCAGGTGC
GCGTTTTTCACCGCCCGCATCCATCGCCCAACACCGATAAAGGCGCGGTGGCCAGCGTGCGCGACTGGCTTAAATCTCAC
GGAGTACATCCATGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10164.64 Da
• Isoelectric Point: 4.3837

>AT216917 WP_032611697.1 NZ_CP083630:1077285-1077551 [Leclercia adecarboxylata]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILDRRVFNFNDEQYAEFIDMLDAPVADDPIIEKLL
ARKPQWDM

Nucleotide

• Length: 267 bp

>AT216917 NZ_CP113517:c2316437-2316102 [Methylomonas rapida]
ATGATTAATCAAATGATGATAGCCGGCGTTAAGGCCGTGATTACTTACGATTCCGACCTCGAGTTGTTTCGCGGTGAGTT
TGTGGGCTTGAGCGGCAGCGCGGACTTTTATGCCGCCGACGTGGCTGGATTGAAGCGCGAAGGTGAAATTTCTTTGCGCG
TGTATCTTGAAGCCTGCCAAGAATCCGGCATAGAACCGTTCAAGGCCTTTTCCGGAAAATTCAACGTGCGCATCCCCGCC
GATTTGCATGCCAGCATCGTCAGCGCGGCGGCGGCCCAAGGCAAAAGCATCAATCAATGGATTGGCGAGGCCTTGAGCCG
CGAGGTGAATGCTTGA

Structures

Antitoxin

• AlphaFold DB: A0A085GLQ4