Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4215649..4216165 Replicon chromosome
Accession NZ_CP083620
Organism Enterobacter bugandensis strain FDAARGOS_1520

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LA316_RS20040 Protein ID WP_088204684.1
Coordinates 4215649..4215933 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8E1RL94
Locus tag LA316_RS20045 Protein ID WP_023331889.1
Coordinates 4215923..4216165 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LA316_RS20025 (LA316_20025) 4212015..4212587 + 573 WP_088204682.1 fructose PTS transporter subunit IIA -
LA316_RS20030 (LA316_20030) 4212957..4215095 + 2139 WP_048960133.1 anaerobic ribonucleoside-triphosphate reductase -
LA316_RS20035 (LA316_20035) 4215181..4215645 + 465 WP_088204683.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
LA316_RS20040 (LA316_20040) 4215649..4215933 - 285 WP_088204684.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LA316_RS20045 (LA316_20045) 4215923..4216165 - 243 WP_023331889.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LA316_RS20050 (LA316_20050) 4216243..4218153 - 1911 WP_048999489.1 PRD domain-containing protein -
LA316_RS20055 (LA316_20055) 4218173..4219309 - 1137 WP_088204685.1 lactonase family protein -
LA316_RS20060 (LA316_20060) 4219335..4220075 - 741 WP_041911457.1 KDGP aldolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10991.91 Da        Isoelectric Point: 10.0526

>T216901 WP_088204684.1 NZ_CP083620:c4215933-4215649 [Enterobacter bugandensis]
MIYELEFDPRALKEWHKLGDTVKCQFKKKLADVLVNPRIESARLHGLSDCYKIKLRSLGYRLVYQVQDNVVTVFVIAIGK
REKSAVYHEANKRL

Download         Length: 285 bp

>T216901 NZ_CP113504:c1057401-1057096 [Pectobacterium brasiliense]
ATGCAATTCATTGTTTATCTATACAAACGTGCCAGCCACTACAAAATGTTTGTCGATGTGCAAAGCGATATTGTCGACAC
ACCGAAGCGGCGCATGGTCATTCCGCTTATCGAATCACATCACCTGTCTGAGAAAGTGAATAAAACGCTGTTCCCTCTGA
TCCGCATCGATGGCGAAGATTATCGACTGATGACGACTGAACTATCGAGCGTTCCCGTTGAGGTTATTGGTGAAGTGATT
ACAGATCTTGGCGACTGTGCGGATGAGATCAAGGATGCTCTTAATCTTATGTTTTGGGGGATCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9030.41 Da        Isoelectric Point: 4.7719

>AT216901 WP_023331889.1 NZ_CP083620:c4216165-4215923 [Enterobacter bugandensis]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTISDSEDELIQTVRERLANPQKGIKVSLDDL

Download         Length: 243 bp

>AT216901 NZ_CP113504:c1057622-1057404 [Pectobacterium brasiliense]
ATGAAACACCGCGTCAGCGTTACCGTAGACAAAGACAATTATCAGGTTCTGAGTGCTGCCGGAGTCAATATTTCCGGGCT
GGTGAATGATGCCATTGGCAAAGAAGCCCGCCGCATCAAGGCTGAAGAGTGGAAGAAGGAAAACCGCGAAGGGATGGAAG
AAGTCGCCCGATTCATTGCACAGCATGGCTCCTTTGCGGATGAAAACAGGAACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References