Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3117709..3118622 Replicon chromosome
Accession NZ_CP083620
Organism Enterobacter bugandensis strain FDAARGOS_1520

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LA316_RS14890 Protein ID WP_088204937.1
Coordinates 3118149..3118622 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LA316_RS14885 Protein ID WP_045261776.1
Coordinates 3117709..3118152 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LA316_RS14870 (LA316_14870) 3114117..3115838 + 1722 WP_088204938.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -
LA316_RS14875 (LA316_14875) 3115884..3116588 + 705 WP_041910636.1 leucyl/phenylalanyl-tRNA--protein transferase -
LA316_RS14880 (LA316_14880) 3116873..3117091 + 219 WP_002211347.1 translation initiation factor IF-1 -
LA316_RS14885 (LA316_14885) 3117709..3118152 + 444 WP_045261776.1 DUF2384 domain-containing protein Antitoxin
LA316_RS14890 (LA316_14890) 3118149..3118622 + 474 WP_088204937.1 RES domain-containing protein Toxin
LA316_RS14895 (LA316_14895) 3118645..3119199 - 555 WP_088204936.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
LA316_RS14900 (LA316_14900) 3119209..3120207 - 999 WP_045261779.1 type I-F CRISPR-associated protein Csy3 -
LA316_RS14905 (LA316_14905) 3120221..3121156 - 936 WP_088204935.1 type I-F CRISPR-associated protein Csy2 -
LA316_RS14910 (LA316_14910) 3121153..3122463 - 1311 WP_088204934.1 type I-F CRISPR-associated protein Csy1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(30-90)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17531.88 Da        Isoelectric Point: 5.0700

>T216899 WP_088204937.1 NZ_CP083620:3118149-3118622 [Enterobacter bugandensis]
MIFYRLVTGRYASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHIRKDTVLNQYQLFSIDIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQASSALALILPSCIIPYENNAILNPLHPAFHTALSSVQQMPFIFDTRLAEKTAP

Download         Length: 474 bp

>T216899 NZ_CP113504:828715-829089 [Pectobacterium brasiliense]
ATGCAACTGTTATCATTGGTTGTGCATGGCCTATTAGTATTGCTCATTCTGCTGGCACCCTGGCCGGACGGCTATGCGTG
GCTATGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTATCCGTAGCCAACGGAATATTAAATCCCGACAGGGGGAAA
TCGTTCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAGGAATGGCAGATCGTTAAACGACCGTGGTTGCTGAAGAAT
GGCGTATTACTGTCATTGCAAGCGGTTAACGGTAAAGACAAGCAGCAGCTGTGGCTGGCATCGGACAGCATGGGCGATGA
CGAATGGCGCCACTTGCGTCAAATTCTTTTGCAGCAGAAACACTGGGCAAGATAG

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16365.72 Da        Isoelectric Point: 8.5886

>AT216899 WP_045261776.1 NZ_CP083620:3117709-3118152 [Enterobacter bugandensis]
MRTWIPAKKPADNALWRYAGLPANRGMRLIEFLNQGLPVSVLDNIHEWTAMSKADILRVTGINERNVARRKSAGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQSPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp

>AT216899 NZ_CP113504:828429-828695 [Pectobacterium brasiliense]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAATTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTTAATGACACTGATAAGCGCACATTTGTACGCTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGGAGGACGGAGAGCTGAAACGCATGATTTCCCTTATTCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References