Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 71463..72099 Replicon chromosome
Accession NC_008344
Organism Nitrosomonas eutropha C91

Toxin (Protein)


Gene name vapC Uniprot ID Q0AJW2
Locus tag NEUT_RS00375 Protein ID WP_011633204.1
Coordinates 71683..72099 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID Q0AJW3
Locus tag NEUT_RS00370 Protein ID WP_011633203.1
Coordinates 71463..71696 (+) Length 78 a.a.

Genomic Context

NEUT_RS00360NEUT_RS00370NEUT_RS00375NEUT_RS00380NEUT_RS00365NEUT_RS00385NEUT_RS00390NEUT_RS00395NEUT_RS00400
Location: 68874..69281 (408 bp)
Type: Others
Protein ID: WP_049753072.1
Location: 71463..71696 (234 bp)
Type: Antitoxin
Protein ID: WP_011633203.1
Location: 71683..72099 (417 bp)
Type: Toxin
Protein ID: WP_011633204.1
Location: 72119..72487 (369 bp)
Type: Others
Protein ID: WP_041353624.1
Location: 69328..71193 (1866 bp)
Type: Others
Protein ID: WP_011633202.1
Location: 72484..73989 (1506 bp)
Type: Others
Protein ID: WP_011633206.1
Location: 74005..74349 (345 bp)
Type: Others
Protein ID: WP_011633207.1
Location: 74346..75743 (1398 bp)
Type: Others
Protein ID: WP_011633208.1
Location: 75762..76694 (933 bp)
Type: Others
Protein ID: WP_011633209.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NEUT_RS0036068874..69281+408WP_049753072.1Cu(I)-responsive transcriptional regulator-
NEUT_RS0036569328..71193-1866WP_011633202.1TraI domain-containing protein-
NEUT_RS0037071463..71696+234WP_011633203.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
NEUT_RS0037571683..72099+417WP_011633204.1PIN domain-containing proteinToxin
NEUT_RS0038072119..72487+369WP_041353624.1DUF3742 family protein-
NEUT_RS0038572484..73989-1506WP_011633206.1conjugal transfer protein TraG N-terminal domain-containing protein-
NEUT_RS0039074005..74349-345WP_011633207.1hypothetical protein-
NEUT_RS0039574346..75743-1398WP_011633208.1integrating conjugative element protein-
NEUT_RS0040075762..76694-933WP_011633209.1TIGR03756 family integrating conjugative element protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--10240..8380773567


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-120)

Antitoxin

SpoVT-AbrB domain

(5-45)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15521.97 Da        Isoelectric Point: 6.4724

>T21688 WP_011633204.1 NC_008344:71683-72099 [Nitrosomonas eutropha C91]
MRVTKFKHFMDSNVVLYLLSEDSTKADKAESLLKAGPVISVQVLNEVTNVCVRKLKMSWDEIAQFLELIRSFCKVVPLTE
TIHDQARLIAERHKLSFYDSCIVAAAVAAGCQTLYSEDMNHGQILEDSLSLRNPFSTV

Download         Length: 417 bp

>T21688 NC_008344:71683-72099 [Nitrosomonas eutropha C91]
ATGCGCGTGACTAAGTTCAAGCATTTTATGGACAGCAATGTGGTGTTGTACCTGCTGTCGGAGGACTCGACCAAAGCGGA
CAAGGCCGAAAGCCTGCTGAAAGCCGGGCCAGTCATCAGCGTGCAAGTGCTCAACGAAGTGACGAATGTCTGCGTACGCA
AGCTCAAAATGAGCTGGGACGAGATCGCGCAGTTCCTGGAACTGATACGGAGCTTTTGCAAGGTCGTCCCACTCACGGAA
ACCATCCATGATCAGGCCCGATTGATCGCTGAGCGACATAAGCTGTCCTTCTACGACTCCTGCATCGTCGCAGCAGCTGT
GGCAGCGGGTTGCCAGACGCTCTATAGTGAGGACATGAACCACGGGCAGATACTGGAAGATAGCTTGAGTCTCAGGAATC
CATTTTCCACCGTATAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8563.83 Da        Isoelectric Point: 10.1756

>AT21688 WP_011633203.1 NC_008344:71463-71696 [Nitrosomonas eutropha C91]
MQVAKWGNSLAVRLPASLVEALELQEGDDIEIVVDGPRAFAVRKKPGADALLKRLRTFRGKLPADFRFSRDEANARD

Download         Length: 234 bp

>AT21688 NC_008344:71463-71696 [Nitrosomonas eutropha C91]
ATGCAAGTCGCCAAATGGGGCAACAGCTTGGCCGTGCGCCTTCCGGCCAGCCTGGTAGAAGCGCTGGAGTTGCAAGAAGG
TGACGATATTGAGATCGTCGTGGACGGCCCGCGCGCGTTCGCGGTTCGCAAAAAGCCAGGCGCCGATGCCTTGTTGAAGC
GCCTGCGCACCTTCCGGGGCAAACTGCCGGCGGATTTCCGCTTCAGCCGGGACGAGGCCAATGCGCGTGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBQ0AJW2

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBQ0AJW3

References