Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1909518..1910431 Replicon chromosome
Accession NZ_CP083613
Organism Enterobacter hormaechei subsp. oharae strain FDAARGOS_1533

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LA353_RS09090 Protein ID WP_047052345.1
Coordinates 1909518..1909991 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LA353_RS09095 Protein ID WP_047052347.1
Coordinates 1909988..1910431 (-) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LA353_RS09070 (LA353_09065) 1905677..1906987 + 1311 WP_047052339.1 type I-F CRISPR-associated protein Csy1 -
LA353_RS09075 (LA353_09070) 1906984..1907919 + 936 WP_047052340.1 type I-F CRISPR-associated protein Csy2 -
LA353_RS09080 (LA353_09075) 1907933..1908931 + 999 WP_047052342.1 type I-F CRISPR-associated protein Csy3 -
LA353_RS09085 (LA353_09080) 1908941..1909495 + 555 WP_047052344.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
LA353_RS09090 (LA353_09085) 1909518..1909991 - 474 WP_047052345.1 RES domain-containing protein Toxin
LA353_RS09095 (LA353_09090) 1909988..1910431 - 444 WP_047052347.1 DUF2384 domain-containing protein Antitoxin
LA353_RS09100 (LA353_09095) 1912383..1912601 - 219 WP_002211347.1 translation initiation factor IF-1 -
LA353_RS09105 (LA353_09100) 1912886..1913590 - 705 WP_047052381.1 leucyl/phenylalanyl-tRNA--protein transferase -
LA353_RS09110 (LA353_09105) 1913636..1915357 - 1722 WP_003858307.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-144)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17570.95 Da        Isoelectric Point: 5.1151

>T216864 WP_047052345.1 NZ_CP083613:c1909991-1909518 [Enterobacter hormaechei subsp. oharae]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFDFDTRLAEKTAP

Download         Length: 474 bp

>T216864 NZ_CP113498:c786694-786398 [Mycoplasma feriruminatoris]
ATGACTAAATATAAAATTGTTTGAACAACAAAATTTAAAAAGGATTTAAAGCTAGCTAAAAAACAGAACAAAGATTTAAA
TAAACTAGACTATGTTATTAATATATTAATTCAAGGCAAAGAGTTAGACGCAAAATATCAGGATCATTCATTTACTGGCA
TTTATAAAGAATATAGAGAGTGTCATATTGACCCTGACTGACTTTTAATATATAAAAAAGATGATGATAAAATTGTTATA
ATAATGTTAAGATTAGGTTCACATTCTAATTTATTTGAAAAACAAAAAAACTACTAG

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16502.77 Da        Isoelectric Point: 6.4819

>AT216864 WP_047052347.1 NZ_CP083613:c1910431-1909988 [Enterobacter hormaechei subsp. oharae]
MRTWVPAQRSADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp

>AT216864 NZ_CP113498:c786959-786687 [Mycoplasma feriruminatoris]
ATGAAAACAACAAATTTAAACGTAAGAATTGATAAAGAAGTCAAACATGATGCAGAAGCTATATTTAATGAATTGGGTTT
AAGCACATCAGCAGCTATAAATATGTTTTTTAAGGCTACAATTAGAAATAACAGTCTTCCTTTTAGCACTAAACTGGATA
CTCCTAATAAAGAAACTTTGTTAGCTATGAAAGAAGCAGAAGAACTATTAAAAGATCCAAATACAAAGTATTATTCAAGC
TTTAAAGAACTTTTAGAGACATTAGATGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References