21683

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 3409648..3410317 Replicon chromosome
Accession NC_008321
Organism Shewanella sp. MR-4

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag SHEWMR4_RS14975 Protein ID WP_011623606.1
Coordinates 3409648..3410088 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag SHEWMR4_RS14980 Protein ID WP_083757995.1
Coordinates 3410069..3410317 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SHEWMR4_RS14950 3405071..3405544 - 474 WP_011623601.1 SoxR reducing system RseC family protein -
SHEWMR4_RS14955 3405556..3406488 - 933 WP_011623602.1 MucB/RseB C-terminal domain-containing protein -
SHEWMR4_RS14960 3406501..3407124 - 624 WP_011623603.1 anti-sigma factor -
SHEWMR4_RS14965 3407151..3407729 - 579 WP_011623604.1 RNA polymerase sigma factor RpoE -
SHEWMR4_RS14970 3407919..3409532 + 1614 WP_011623605.1 L-aspartate oxidase -
SHEWMR4_RS14975 3409648..3410088 - 441 WP_011623606.1 hypothetical protein Toxin
SHEWMR4_RS14980 3410069..3410317 - 249 WP_083757995.1 succinate dehydrogenase assembly factor 2 Antitoxin
SHEWMR4_RS14985 3410401..3411309 - 909 WP_011623608.1 transcriptional activator NhaR -
SHEWMR4_RS14990 3411405..3411791 - 387 WP_011623609.1 hypothetical protein -
SHEWMR4_RS14995 3411794..3412963 - 1170 WP_011623610.1 Na+/H+ antiporter NhaA -
SHEWMR4_RS15000 3413081..3413875 - 795 WP_011623611.1 thymidylate synthase -
SHEWMR4_RS15005 3413875..3414681 - 807 WP_011623612.1 prolipoprotein diacylglyceryl transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-134)

Antitoxin

Flavinator of succinate dehydrogenase

(7-77)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 17021.01 Da        Isoelectric Point: 8.9501

>T21683 WP_011623606.1 NC_008321:c3410088-3409648 [Shewanella sp. MR-4]
VAERRHSFSVKASFDQRLSLVVFVCVCGTSLLIWPETDVVFWLVLKLVFAVLILGFLGYQLWRLRTWHCRFELNGKGKGW
LSTGEAFHVLPRTWVTPFVCLVYYQSADKLHLLPLWADMFSDTDYRHLCRLLLKVKTQAASQSEHF

Download         Length: 441 bp

>T21683 NC_008321:c3410088-3409648 [Shewanella sp. MR-4]
GTGGCAGAGCGGCGCCATAGTTTTAGTGTAAAAGCCTCCTTCGACCAGCGACTCTCGTTGGTCGTTTTTGTTTGTGTCTG
CGGTACCTCTTTACTGATCTGGCCTGAAACAGATGTCGTATTTTGGCTTGTGCTTAAGTTGGTATTCGCCGTTTTAATCC
TCGGATTCTTGGGCTATCAGTTATGGCGACTGAGGACTTGGCATTGCCGTTTTGAGCTCAATGGGAAAGGGAAAGGCTGG
CTCTCGACGGGGGAGGCGTTCCATGTGCTCCCCAGAACTTGGGTAACGCCCTTTGTTTGCTTAGTTTACTATCAGTCCGC
CGATAAGTTGCATCTTTTACCCCTTTGGGCCGATATGTTTAGCGATACGGATTACCGCCACTTGTGCCGGCTATTGCTTA
AGGTTAAAACTCAGGCTGCGAGCCAAAGCGAACATTTTTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9599.15 Da        Isoelectric Point: 4.3440

>AT21683 WP_083757995.1 NC_008321:c3410317-3410069 [Shewanella sp. MR-4]
MELMNIARVRWACRRGMLELDVLFQPFVENVYQDLSDEDKALFIRLLECEDPELFAWFMGHEACPDPELARMVVQVRGRA
AP

Download         Length: 249 bp

>AT21683 NC_008321:c3410317-3410069 [Shewanella sp. MR-4]
TTGGAGTTAATGAACATTGCACGGGTCCGCTGGGCATGTCGCCGCGGAATGCTCGAATTAGACGTCTTGTTCCAGCCTTT
CGTCGAAAATGTTTATCAGGACTTGTCAGATGAAGACAAGGCCCTGTTTATACGTTTACTCGAGTGCGAAGATCCTGAAT
TATTTGCCTGGTTTATGGGTCATGAAGCCTGCCCAGATCCTGAGCTTGCCCGTATGGTAGTGCAAGTCCGTGGCAGAGCG
GCGCCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References