Detailed information of TA system TA021682

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 355301..355851
• Replicon: chromosome
• Accession: NC_008321
• Organism: Shewanella sp. MR-4

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: SHEWMR4_RS01765
• Protein ID: WP_011621138.1
• Coordinates: 355301..355600 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: SHEWMR4_RS01770
• Protein ID: WP_011621139.1
• Coordinates: 355609..355851 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SHEWMR4_RS01740	351382..351978	-	597	WP_011621133.1	SCO family protein	-
SHEWMR4_RS01745	352216..352671	-	456	WP_011621134.1	GNAT family N-acetyltransferase	-
SHEWMR4_RS01750	352957..353388	-	432	WP_011621135.1	hypothetical protein	-
SHEWMR4_RS01755	353443..353913	-	471	WP_011621136.1	hypothetical protein	-
SHEWMR4_RS01760	353988..354866	-	879	WP_157037021.1	hypothetical protein	-
SHEWMR4_RS01765	355301..355600	-	300	WP_011621138.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SHEWMR4_RS01770	355609..355851	-	243	WP_011621139.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
SHEWMR4_RS01775	356036..356779	-	744	WP_011621140.1	hypothetical protein	-
SHEWMR4_RS01780	356790..358043	-	1254	WP_011621141.1	beta-ketoacyl-ACP synthase	-
SHEWMR4_RS01785	358044..358769	-	726	WP_011621142.1	3-ketoacyl-ACP reductase FabG2	-
SHEWMR4_RS01790	358895..359434	-	540	WP_011621143.1	hotdog family protein	-
SHEWMR4_RS01795	359440..360663	-	1224	WP_011621144.1	beta-ketoacyl-[acyl-carrier-protein] synthase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-64)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11504.26 Da
• Isoelectric Point: 9.9435

>T21682 WP_011621138.1 NC_008321:c355600-355301 [Shewanella sp. MR-4]
MNNKRYKLSRLAQIHLQQIKDYTLQHFSESQWHKYKESLISGLQMLANNPGLGRSCNDIYPNGFFFPIGKHTAYFTKEAD
FILIVALLGQPQLPQNHLK

Nucleotide

• Length: 300 bp

>T21682 NC_008321:c355600-355301 [Shewanella sp. MR-4]
ATGAATAATAAACGCTATAAACTGAGTAGGTTAGCTCAGATTCACCTACAACAGATTAAAGACTACACCCTTCAACACTT
TTCTGAGTCGCAGTGGCACAAATATAAAGAAAGCCTTATCTCCGGTTTGCAAATGTTAGCCAATAACCCCGGATTAGGCA
GAAGCTGCAACGATATTTATCCCAACGGTTTCTTCTTTCCTATAGGTAAACACACCGCCTACTTCACCAAAGAAGCCGAC
TTTATCCTTATCGTTGCCCTGTTAGGTCAACCACAACTACCCCAAAATCATCTGAAATAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8954.18 Da
• Isoelectric Point: 5.0621

>AT21682 WP_011621139.1 NC_008321:c355851-355609 [Shewanella sp. MR-4]
MQTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAKGNVVDGEDFLNAL

Nucleotide

• Length: 243 bp

>AT21682 NC_008321:c355851-355609 [Shewanella sp. MR-4]
ATGCAAACCTTAACCGCCAATGACGCCAAACGAAATTTTGGTGAGTTGCTTCTAAACGCTCAACGCGAACCCATCAAGAT
CAGCAAAAACAGTAAAGATGCGGTTGTGGTCATGTCTATCCACGATTACGAACAGCTTGAGGCGATGAAAGCCGACTATC
TGAAGCACTGTTTCAACGCAGCCAAAGAAGATTTAGCGAAGGGCAATGTGGTTGATGGTGAAGATTTTCTTAACGCCCTG
TAG