Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 355301..355851 Replicon chromosome
Accession NC_008321
Organism Shewanella sp. MR-4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag SHEWMR4_RS01765 Protein ID WP_011621138.1
Coordinates 355301..355600 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag SHEWMR4_RS01770 Protein ID WP_011621139.1
Coordinates 355609..355851 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SHEWMR4_RS01740 351382..351978 - 597 WP_011621133.1 SCO family protein -
SHEWMR4_RS01745 352216..352671 - 456 WP_011621134.1 GNAT family N-acetyltransferase -
SHEWMR4_RS01750 352957..353388 - 432 WP_011621135.1 hypothetical protein -
SHEWMR4_RS01755 353443..353913 - 471 WP_011621136.1 hypothetical protein -
SHEWMR4_RS01760 353988..354866 - 879 WP_157037021.1 hypothetical protein -
SHEWMR4_RS01765 355301..355600 - 300 WP_011621138.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SHEWMR4_RS01770 355609..355851 - 243 WP_011621139.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
SHEWMR4_RS01775 356036..356779 - 744 WP_011621140.1 hypothetical protein -
SHEWMR4_RS01780 356790..358043 - 1254 WP_011621141.1 beta-ketoacyl-ACP synthase -
SHEWMR4_RS01785 358044..358769 - 726 WP_011621142.1 3-ketoacyl-ACP reductase FabG2 -
SHEWMR4_RS01790 358895..359434 - 540 WP_011621143.1 hotdog family protein -
SHEWMR4_RS01795 359440..360663 - 1224 WP_011621144.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-64)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11504.26 Da        Isoelectric Point: 9.9435

>T21682 WP_011621138.1 NC_008321:c355600-355301 [Shewanella sp. MR-4]
MNNKRYKLSRLAQIHLQQIKDYTLQHFSESQWHKYKESLISGLQMLANNPGLGRSCNDIYPNGFFFPIGKHTAYFTKEAD
FILIVALLGQPQLPQNHLK

Download         Length: 300 bp

>T21682 NC_008321:c355600-355301 [Shewanella sp. MR-4]
ATGAATAATAAACGCTATAAACTGAGTAGGTTAGCTCAGATTCACCTACAACAGATTAAAGACTACACCCTTCAACACTT
TTCTGAGTCGCAGTGGCACAAATATAAAGAAAGCCTTATCTCCGGTTTGCAAATGTTAGCCAATAACCCCGGATTAGGCA
GAAGCTGCAACGATATTTATCCCAACGGTTTCTTCTTTCCTATAGGTAAACACACCGCCTACTTCACCAAAGAAGCCGAC
TTTATCCTTATCGTTGCCCTGTTAGGTCAACCACAACTACCCCAAAATCATCTGAAATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8954.18 Da        Isoelectric Point: 5.0621

>AT21682 WP_011621139.1 NC_008321:c355851-355609 [Shewanella sp. MR-4]
MQTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAKGNVVDGEDFLNAL

Download         Length: 243 bp

>AT21682 NC_008321:c355851-355609 [Shewanella sp. MR-4]
ATGCAAACCTTAACCGCCAATGACGCCAAACGAAATTTTGGTGAGTTGCTTCTAAACGCTCAACGCGAACCCATCAAGAT
CAGCAAAAACAGTAAAGATGCGGTTGTGGTCATGTCTATCCACGATTACGAACAGCTTGAGGCGATGAAAGCCGACTATC
TGAAGCACTGTTTCAACGCAGCCAAAGAAGATTTAGCGAAGGGCAATGTGGTTGATGGTGAAGATTTTCTTAACGCCCTG
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References