Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1995364..1995635 Replicon chromosome
Accession NZ_CP083585
Organism Escherichia coli strain ECNB21-M121

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1995494..1995597 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1995364..1995635 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LA372_RS09560 1991919..1992581 - 663 WP_000944256.1 exodeoxyribonuclease X -
LA372_RS09565 1992605..1993261 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein YobB -
LA372_RS09570 1993363..1993593 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LA372_RS09575 1993732..1994106 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LA372_RS09580 1994110..1994982 + 873 WP_047623971.1 copper homeostasis membrane protein CopD -
LA372_RS09585 1994995..1995336 + 342 WP_000976472.1 YebY family protein -
- 1995364..1995635 - 272 - - Antitoxin
- 1995494..1995597 + 104 - - Toxin
LA372_RS09590 1995732..1996388 + 657 WP_047623972.1 protein-serine/threonine phosphatase -
LA372_RS09595 1996389..1996580 - 192 WP_001296140.1 YebW family protein -
LA372_RS09600 1996685..1996921 - 237 WP_047623973.1 YebV family protein -
LA372_RS09605 1997039..1998478 - 1440 WP_047624031.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1971653..2011478 39825


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T216776 NZ_CP083585:1995494-1995597 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT216776 NZ_CP083585:c1995635-1995364 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References