216759

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4518839..4519200 Replicon chromosome
Accession NZ_CP083575
Organism Xanthomonas phaseoli pv. manihotis strain CHN01

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag K9838_RS19900 Protein ID WP_005914328.1
Coordinates 4518839..4518973 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag K9838_RS19905 Protein ID WP_003486606.1
Coordinates 4519048..4519200 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9838_RS19880 (K9838_19890) 4515545..4515799 + 255 WP_017158234.1 hypothetical protein -
K9838_RS19885 (K9838_19895) 4515867..4516943 - 1077 WP_017158235.1 MBL fold metallo-hydrolase -
K9838_RS19890 (K9838_19900) 4516940..4518229 - 1290 WP_017158236.1 tryptophan--tRNA ligase -
K9838_RS19895 (K9838_19905) 4518399..4518608 - 210 Protein_3908 CsbD family protein -
K9838_RS19900 (K9838_19910) 4518839..4518973 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
K9838_RS19905 (K9838_19915) 4519048..4519200 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
K9838_RS19910 (K9838_19920) 4519307..4520230 - 924 WP_017158237.1 arginase -
K9838_RS19915 (K9838_19925) 4520551..4521003 + 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
K9838_RS19920 (K9838_19930) 4521145..4521426 + 282 WP_228508037.1 roadblock/LC7 domain-containing protein -
K9838_RS19925 (K9838_19935) 4521523..4522440 + 918 WP_017158239.1 hypothetical protein -
K9838_RS19930 (K9838_19940) 4522437..4522990 + 554 Protein_3915 GTPase -
K9838_RS19935 (K9838_19945) 4523502..4524185 + 684 WP_017158240.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T216759 WP_005914328.1 NZ_CP083575:c4518973-4518839 [Xanthomonas phaseoli pv. manihotis]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T216759 NZ_CP113364:3399761-3399979 [Salmonella enterica subsp. enterica]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT216759 WP_003486606.1 NZ_CP083575:c4519200-4519048 [Xanthomonas phaseoli pv. manihotis]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT216759 NZ_CP113364:3399359-3399733 [Salmonella enterica subsp. enterica]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References