Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 796281..797749 Replicon chromosome
Accession NZ_CP083454
Organism Stenotrophomonas maltophilia strain XL133

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag LAD79_RS03620 Protein ID WP_157803285.1
Coordinates 796281..797150 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag LAD79_RS03625 Protein ID WP_032966430.1
Coordinates 797147..797749 (-) Length 201 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LAD79_RS03600 (LAD79_03600) 792459..793037 - 579 WP_100438875.1 metal-dependent hydrolase -
LAD79_RS03605 (LAD79_03605) 793148..793516 - 369 WP_012479149.1 YraN family protein -
LAD79_RS03610 (LAD79_03610) 793506..795227 - 1722 WP_049459446.1 penicillin-binding protein activator -
LAD79_RS03615 (LAD79_03615) 795309..796127 + 819 WP_060381104.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
LAD79_RS03620 (LAD79_03620) 796281..797150 - 870 WP_157803285.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LAD79_RS03625 (LAD79_03625) 797147..797749 - 603 WP_032966430.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LAD79_RS03635 (LAD79_03635) 798500..798979 - 480 WP_100438877.1 DM13 domain-containing protein -
LAD79_RS03640 (LAD79_03640) 799297..800049 - 753 WP_100438888.1 NRDE family protein -
LAD79_RS03645 (LAD79_03645) 800373..800819 + 447 WP_004143635.1 division/cell wall cluster transcriptional repressor MraZ -
LAD79_RS03650 (LAD79_03650) 800834..801802 + 969 WP_012479154.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
LAD79_RS03655 (LAD79_03655) 801799..802062 + 264 WP_005412242.1 cell division protein FtsL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 783445..798979 15534


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(40-268)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(12-53)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32579.23 Da        Isoelectric Point: 6.3012

>T216476 WP_157803285.1 NZ_CP083454:c797150-796281 [Stenotrophomonas maltophilia]
VTHSPPLPQRVASIRQRLLDLARSRGEDFQFVLDRFAVERLLYRLSASRYRDQFLLKGAMLFAVWFDAPHRPTRDADFLR
FGSADPDHLLHIARSLCAIPDDDGLCFDPGSIAIEATREEAEYEGLRIRLTAHLGRSRCHVQWDVGFGDAVTPPPPEIAY
PVMLDGFPLPCLHVYPRETVFAEKLEAIAALGIANSRMKDFFDLLALVREDAMDRPHLVAAIGATFDRRRTPAPPPLPYG
LTQSFAADTQKQTQWRAFLRRNRLIAPDLSSVIAEIADYLDTLDTTVQS

Download         Length: 870 bp

>T216476 NZ_CP113074:614351-614740 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAACTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCATTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAAAACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAACAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 201 a.a.        Molecular weight: 22331.07 Da        Isoelectric Point: 11.2557

>AT216476 WP_032966430.1 NZ_CP083454:c797749-797147 [Stenotrophomonas maltophilia]
MGNAEANARKLLRRAGTLRARELVTAGIARAQLTRLVEAGALIRLSRGVYALAERNSDDTDDGLRIIAERLPHPRLCLLS
ALRLHGLTTQAPFERWVSIGNSDRVPRIDWPPLRVVRMSAKTLNAGLEERRVGKRLIYVSNVAKTVVDCFKFRNLVGLDV
AIEALRDALHSRATTPDALMEYARICRVARLMRPYLDALA

Download         Length: 603 bp

>AT216476 NZ_CP113074:614087-614344 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References