Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4456913..4457058 Replicon chromosome
Accession NZ_CP083445
Organism Klebsiella pneumoniae strain KP294

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4456949..4457051 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4456913..4457058 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LAV94_RS21690 4452043..4454103 + 2061 WP_004151449.1 oligopeptidase B -
LAV94_RS21695 4454107..4454766 - 660 WP_002911407.1 exodeoxyribonuclease X -
LAV94_RS21700 4454845..4455075 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LAV94_RS21705 4455188..4455562 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LAV94_RS21710 4455566..4456435 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LAV94_RS21715 4456452..4456790 + 339 WP_004189269.1 YebY family protein -
- 4456913..4457058 - 146 - - Antitoxin
- 4456949..4457051 + 103 - - Toxin
LAV94_RS21720 4457425..4457568 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LAV94_RS21725 4457673..4458641 - 969 WP_004151446.1 VirK/YbjX family protein -
LAV94_RS21730 4458798..4459451 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
LAV94_RS21735 4459448..4459639 - 192 WP_002911395.1 YebW family protein -
LAV94_RS21740 4459737..4459976 - 240 WP_002911393.1 YebV family protein -
LAV94_RS21745 4460092..4461525 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T216457 NZ_CP083445:4456949-4457051 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT216457 NZ_CP083445:c4457058-4456913 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References