Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2151663..2151808 Replicon chromosome
Accession NZ_CP083443
Organism Klebsiella pneumoniae strain KP1711R

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2151699..2151801 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2151663..2151808 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9870_RS10430 2146793..2148853 + 2061 WP_004151449.1 oligopeptidase B -
K9870_RS10435 2148857..2149516 - 660 WP_020324964.1 exodeoxyribonuclease X -
K9870_RS10440 2149595..2149825 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K9870_RS10445 2149938..2150312 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K9870_RS10450 2150316..2151185 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K9870_RS10455 2151202..2151540 + 339 WP_002911404.1 YebY family protein -
- 2151663..2151808 - 146 - - Antitoxin
- 2151699..2151801 + 103 - - Toxin
K9870_RS10460 2152177..2152320 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K9870_RS10465 2152425..2153393 - 969 WP_004151446.1 VirK/YbjX family protein -
K9870_RS10470 2153550..2154203 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K9870_RS10475 2154200..2154391 - 192 WP_002911395.1 YebW family protein -
K9870_RS10480 2154489..2154728 - 240 WP_002911393.1 YebV family protein -
K9870_RS10485 2154844..2156277 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T216429 NZ_CP083443:2151699-2151801 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT216429 NZ_CP083443:c2151808-2151663 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References