Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mbcAT/RES-TIGR02293
Location 31943..32856 Replicon plasmid pCL-A6099
Accession NZ_CP083440
Organism Clavibacter sp. A6099

Toxin (Protein)


Gene name mbcT Uniprot ID -
Locus tag KYT88_RS15745 Protein ID WP_237583859.1
Coordinates 32350..32856 (+) Length 169 a.a.

Antitoxin (Protein)


Gene name mbcA Uniprot ID -
Locus tag KYT88_RS15740 Protein ID WP_043588246.1
Coordinates 31943..32293 (+) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KYT88_RS15720 (KYT88_15735) 28018..28830 + 813 WP_147362292.1 HIRAN domain-containing protein -
KYT88_RS15725 (KYT88_15740) 28960..29208 + 249 WP_043588162.1 hypothetical protein -
KYT88_RS15730 (KYT88_15745) 29236..29742 + 507 WP_237583858.1 hypothetical protein -
KYT88_RS15735 (KYT88_15755) 30697..31857 - 1161 WP_043588164.1 hypothetical protein -
KYT88_RS15740 (KYT88_15760) 31943..32293 + 351 WP_043588246.1 DUF2384 domain-containing protein Antitoxin
KYT88_RS15745 (KYT88_15765) 32350..32856 + 507 WP_237583859.1 RES domain-containing protein Toxin
KYT88_RS15750 (KYT88_15770) 32967..33176 + 210 WP_043588166.1 hypothetical protein -
KYT88_RS15755 (KYT88_15775) 33202..33738 + 537 WP_051629425.1 Fic family protein -
KYT88_RS15760 (KYT88_15780) 33774..34682 - 909 WP_051629426.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
KYT88_RS15765 (KYT88_15785) 34675..35724 - 1050 WP_081840997.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
KYT88_RS15770 (KYT88_15790) 35979..36467 + 489 WP_051629428.1 hypothetical protein -
KYT88_RS15775 (KYT88_15795) 36526..36867 - 342 WP_043588170.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..64853 64853


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(12-139)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(74-113)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18195.47 Da        Isoelectric Point: 4.9999

>T216416 WP_237583859.1 NZ_CP083440:32350-32856 [Clavibacter sp. A6099]
VSGTYYRYSSARREPLSGAGARAFGGRWNPRGLFPAIYLAEPKESCAGEARRAAEALGTSAEVMLEAPFMLHTIEVNEVS
VLNLTTDEALEHVGLSREDIADNDHTACRAVGHAAWFLGFQGVLAPSASEVGFVLAAFEGRLDMRHLRVDQSEPFTPALY
STLAPALW

Download         Length: 507 bp

>T216416 NZ_CP113042:c1763069-1762881 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTAGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 12518.29 Da        Isoelectric Point: 5.0878

>AT216416 WP_043588246.1 NZ_CP083440:31943-32293 [Clavibacter sp. A6099]
MSAVSATALASKVVGIYDRLGLTQEEIGGIVDASARSVSRWVTGQVVPQRLNKARLLELAYVADAVAEVLPASQANVWMF
SPSRLLDHDTPAERIHKGQYRDVLDLIEAIADGAFV

Download         Length: 351 bp

>AT216416 NZ_CP113042:c1763358-1763098 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References