Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 509738..510254 Replicon chromosome
Accession NZ_CP083403
Organism Enterobacter bugandensis strain XL95

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K9O83_RS02455 Protein ID WP_041911453.1
Coordinates 509970..510254 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K9O83_RS02450 Protein ID WP_041911454.1
Coordinates 509738..509980 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9O83_RS02435 (K9O83_02440) 505828..506568 + 741 WP_028015300.1 KDGP aldolase family protein -
K9O83_RS02440 (K9O83_02445) 506594..507730 + 1137 WP_047367002.1 lactonase family protein -
K9O83_RS02445 (K9O83_02450) 507750..509660 + 1911 WP_224066199.1 PRD domain-containing protein -
K9O83_RS02450 (K9O83_02455) 509738..509980 + 243 WP_041911454.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
K9O83_RS02455 (K9O83_02460) 509970..510254 + 285 WP_041911453.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K9O83_RS02460 (K9O83_02465) 510258..510722 - 465 WP_049138568.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
K9O83_RS02465 (K9O83_02470) 510808..512946 - 2139 WP_224066200.1 anaerobic ribonucleoside-triphosphate reductase -
K9O83_RS02470 (K9O83_02475) 513316..513888 - 573 WP_088204682.1 fructose PTS transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11001.95 Da        Isoelectric Point: 10.0526

>T216340 WP_041911453.1 NZ_CP083403:509970-510254 [Enterobacter bugandensis]
MIYELEFDPRALKEWHKLGDTVKCQFKKKLADVLVNPRIESARLHGLPDCYKIKLRSLGYRLVYQVQDNVVTVFVIAIGK
REKSAVYHEANKRL

Download         Length: 285 bp

>T216340 NZ_CP113018:703529-703795 [Staphylococcus aureus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCAGCGAAATCAGATTTAAAGAAAATAAAACATTCTTATTTAAAGAAGTC
ATTTTTAGAAATTGTTGAGACTTTAAAAAATGATCCGTATAAAATAACACAATCTTTTGAAAAATTAGAGCCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCATCAGCACAGGGTCGTCTATACCGTAGATGATCGAAATAAAGAAGTATTAATA
CTATCGGCATGGTCACATTATGATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9044.43 Da        Isoelectric Point: 4.7719

>AT216340 WP_041911454.1 NZ_CP083403:509738-509980 [Enterobacter bugandensis]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTISDSEDELIQTVRERLANPQKGIKLSLDDL

Download         Length: 243 bp

>AT216340 NZ_CP113018:703272-703529 [Staphylococcus aureus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAACCAAT
TTATATTAGTGGCAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGAAGATTGGAAAAGTATACAAGAGACAATAT
ATCTTGAATCTACTGGTACAATGGACAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References