Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1834916..1835184 Replicon chromosome
Accession NC_008253
Organism Escherichia coli 536

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1834954..1835056 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1834916..1835184 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECP_RS09115 1832073..1833512 + 1440 WP_024174322.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECP_RS09120 1833630..1833866 + 237 WP_001295499.1 DUF1480 family protein -
ECP_RS09125 1833971..1834162 + 192 WP_001296140.1 YebW family protein -
ECP_RS09130 1834163..1834819 - 657 WP_000812743.1 protein-serine/threonine phosphatase -
- 1834916..1835184 + 269 - - Antitoxin
- 1834954..1835056 - 103 - - Toxin
ECP_RS09140 1835214..1835555 - 342 WP_000984819.1 YebY family protein -
ECP_RS09145 1835568..1836440 - 873 WP_000879311.1 copper homeostasis membrane protein CopD -
ECP_RS09150 1836444..1836818 - 375 WP_000168747.1 CopC domain-containing protein YobA -
ECP_RS09155 1836957..1837187 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ECP_RS09160 1837290..1837946 + 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
ECP_RS09165 1837970..1838632 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T21619 NC_008253:c1835056-1834954 [Escherichia coli 536]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT21619 NC_008253:1834916-1835184 [Escherichia coli 536]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References