Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1903331..1903476 Replicon chromosome
Accession NZ_CP083070
Organism Klebsiella pneumoniae strain 1230_0791_KP

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1903367..1903469 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1903331..1903476 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9F20_RS09230 1898461..1900521 + 2061 WP_004151449.1 oligopeptidase B -
K9F20_RS09235 1900525..1901184 - 660 WP_002911407.1 exodeoxyribonuclease X -
K9F20_RS09240 1901263..1901493 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K9F20_RS09245 1901606..1901980 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K9F20_RS09250 1901984..1902853 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
K9F20_RS09255 1902870..1903208 + 339 WP_002911404.1 YebY family protein -
- 1903331..1903476 - 146 - - Antitoxin
- 1903367..1903469 + 103 - - Toxin
K9F20_RS09260 1903844..1903987 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K9F20_RS09265 1904092..1905060 - 969 WP_014907334.1 VirK/YbjX family protein -
K9F20_RS09270 1905217..1905870 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
K9F20_RS09275 1905867..1906058 - 192 WP_002911395.1 YebW family protein -
K9F20_RS09280 1906156..1906395 - 240 WP_002911393.1 YebV family protein -
K9F20_RS09285 1906511..1907944 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T216110 NZ_CP083070:1903367-1903469 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT216110 NZ_CP083070:c1903476-1903331 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References