Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1970757..1970902 Replicon chromosome
Accession NZ_CP083055
Organism Klebsiella pneumoniae strain 1613258639

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1970793..1970895 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1970757..1970902 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9F40_RS09555 1965887..1967947 + 2061 WP_105446489.1 oligopeptidase B -
K9F40_RS09560 1967951..1968610 - 660 WP_002911407.1 exodeoxyribonuclease X -
K9F40_RS09565 1968689..1968919 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K9F40_RS09570 1969032..1969406 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K9F40_RS09575 1969410..1970279 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
K9F40_RS09580 1970296..1970634 + 339 WP_002911404.1 YebY family protein -
- 1970757..1970902 - 146 - - Antitoxin
- 1970793..1970895 + 103 - - Toxin
K9F40_RS09585 1971271..1971414 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K9F40_RS09590 1971519..1972487 - 969 WP_004151446.1 VirK/YbjX family protein -
K9F40_RS09595 1972644..1973297 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K9F40_RS09600 1973294..1973485 - 192 WP_002911395.1 YebW family protein -
K9F40_RS09605 1973583..1973822 - 240 WP_002911393.1 YebV family protein -
K9F40_RS09610 1973938..1975371 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1900194..1975326 75132


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T216050 NZ_CP083055:1970793-1970895 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT216050 NZ_CP083055:c1970902-1970757 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References