Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2055160..2055305 Replicon chromosome
Accession NZ_CP083047
Organism Klebsiella pneumoniae strain 400195-1-18

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2055196..2055298 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2055160..2055305 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9F24_RS10070 2050290..2052350 + 2061 WP_152133137.1 oligopeptidase B -
K9F24_RS10075 2052354..2053013 - 660 WP_043906809.1 exodeoxyribonuclease X -
K9F24_RS10080 2053092..2053322 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K9F24_RS10085 2053435..2053809 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K9F24_RS10090 2053813..2054682 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K9F24_RS10095 2054699..2055037 + 339 WP_002911404.1 YebY family protein -
- 2055160..2055305 - 146 - - Antitoxin
- 2055196..2055298 + 103 - - Toxin
K9F24_RS10100 2055674..2055817 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K9F24_RS10105 2055922..2056890 - 969 WP_004151446.1 VirK/YbjX family protein -
K9F24_RS10110 2057047..2057700 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K9F24_RS10115 2057697..2057888 - 192 WP_002911395.1 YebW family protein -
K9F24_RS10120 2057986..2058225 - 240 WP_002911393.1 YebV family protein -
K9F24_RS10125 2058341..2059774 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1982105..2062531 80426


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T216008 NZ_CP083047:2055196-2055298 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT216008 NZ_CP083047:c2055305-2055160 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References