Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2055044..2055189 Replicon chromosome
Accession NZ_CP083043
Organism Klebsiella pneumoniae strain 400195-2-18

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2055080..2055182 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2055044..2055189 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9F25_RS10070 2050174..2052234 + 2061 WP_152133137.1 oligopeptidase B -
K9F25_RS10075 2052238..2052897 - 660 WP_043906809.1 exodeoxyribonuclease X -
K9F25_RS10080 2052976..2053206 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K9F25_RS10085 2053319..2053693 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K9F25_RS10090 2053697..2054566 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K9F25_RS10095 2054583..2054921 + 339 WP_002911404.1 YebY family protein -
- 2055044..2055189 - 146 - - Antitoxin
- 2055080..2055182 + 103 - - Toxin
K9F25_RS10100 2055558..2055701 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K9F25_RS10105 2055806..2056774 - 969 WP_004151446.1 VirK/YbjX family protein -
K9F25_RS10110 2056931..2057584 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K9F25_RS10115 2057581..2057772 - 192 WP_002911395.1 YebW family protein -
K9F25_RS10120 2057870..2058109 - 240 WP_002911393.1 YebV family protein -
K9F25_RS10125 2058225..2059658 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1981989..2072585 90596


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T215987 NZ_CP083043:2055080-2055182 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT215987 NZ_CP083043:c2055189-2055044 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References