Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2619143..2619237 Replicon chromosome
Accession NC_008149
Organism Yersinia pestis Nepal516

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2619144..2619237 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2619143..2619237 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
YPN_RS12295 2614336..2616414 - 2079 WP_002211100.1 flagellar biosynthesis protein FlhA -
YPN_RS12300 2616414..2617574 - 1161 WP_002211099.1 flagellar type III secretion system protein FlhB -
YPN_RS12305 2618106..2618564 + 459 WP_002211098.1 hypothetical protein -
YPN_RS12310 2618558..2618884 + 327 WP_002211097.1 DUF1493 family protein -
- 2619143..2619237 + 95 - - Antitoxin
- 2619144..2619237 - 94 - - Toxin
YPN_RS12320 2619407..2619748 - 342 WP_002211095.1 YebY family protein -
YPN_RS12325 2619845..2620729 - 885 WP_002211094.1 copper homeostasis membrane protein CopD -
YPN_RS12330 2620732..2621118 - 387 WP_002211093.1 CopC domain-containing protein YobA -
YPN_RS12335 2621524..2622033 - 510 WP_002211092.1 non-heme ferritin -
YPN_RS12340 2622434..2622664 + 231 WP_002211091.1 DNA polymerase III subunit theta -
YPN_RS12345 2622724..2623674 - 951 WP_002211090.1 prolyl aminopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 94 bp

>T21589 NC_008149:c2619237-2619144 [Yersinia pestis Nepal516]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 95 bp

>AT21589 NC_008149:2619143-2619237 [Yersinia pestis Nepal516]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References