Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2020090..2020235 Replicon chromosome
Accession NZ_CP083007
Organism Klebsiella pneumoniae strain 6711.43

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2020126..2020228 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2020090..2020235 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9F29_RS09895 (K9F29_09905) 2015220..2017280 + 2061 WP_032422099.1 oligopeptidase B -
K9F29_RS09900 (K9F29_09910) 2017284..2017943 - 660 WP_002911407.1 exodeoxyribonuclease X -
K9F29_RS09905 (K9F29_09915) 2018022..2018252 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K9F29_RS09910 (K9F29_09920) 2018365..2018739 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K9F29_RS09915 (K9F29_09925) 2018743..2019612 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K9F29_RS09920 (K9F29_09930) 2019629..2019967 + 339 WP_002911404.1 YebY family protein -
- 2020090..2020235 - 146 - - Antitoxin
- 2020126..2020228 + 103 - - Toxin
K9F29_RS09925 (K9F29_09935) 2020603..2020746 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K9F29_RS09930 (K9F29_09940) 2020851..2021819 - 969 WP_004151446.1 VirK/YbjX family protein -
K9F29_RS09935 (K9F29_09945) 2021976..2022629 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K9F29_RS09940 (K9F29_09950) 2022626..2022817 - 192 WP_002911395.1 YebW family protein -
K9F29_RS09945 (K9F29_09955) 2022915..2023154 - 240 WP_002911393.1 YebV family protein -
K9F29_RS09950 (K9F29_09960) 2023270..2024703 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T215858 NZ_CP083007:2020126-2020228 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT215858 NZ_CP083007:c2020235-2020090 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References