Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2104258..2104403 Replicon chromosome
Accession NZ_CP083000
Organism Klebsiella pneumoniae strain 6712.08

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2104294..2104396 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2104258..2104403 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9F30_RS10400 2099388..2101448 + 2061 WP_004151449.1 oligopeptidase B -
K9F30_RS10405 2101452..2102111 - 660 WP_002911407.1 exodeoxyribonuclease X -
K9F30_RS10410 2102190..2102420 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K9F30_RS10415 2102533..2102907 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K9F30_RS10420 2102911..2103780 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
K9F30_RS10425 2103797..2104135 + 339 WP_002911404.1 YebY family protein -
- 2104258..2104403 - 146 - - Antitoxin
- 2104294..2104396 + 103 - - Toxin
K9F30_RS10430 2104771..2104914 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K9F30_RS10435 2105019..2105987 - 969 WP_004151446.1 VirK/YbjX family protein -
K9F30_RS10440 2106144..2106797 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
K9F30_RS10445 2106794..2106985 - 192 WP_002911395.1 YebW family protein -
K9F30_RS10450 2107083..2107322 - 240 WP_002911393.1 YebV family protein -
K9F30_RS10455 2107438..2108871 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T215838 NZ_CP083000:2104294-2104396 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT215838 NZ_CP083000:c2104403-2104258 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References