Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1947883..1948028 Replicon chromosome
Accession NZ_CP082995
Organism Klebsiella pneumoniae strain 6911.28

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1947919..1948021 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1947883..1948028 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9F31_RS09580 (K9F31_09575) 1943013..1945073 + 2061 WP_004151449.1 oligopeptidase B -
K9F31_RS09585 (K9F31_09580) 1945077..1945736 - 660 WP_002911407.1 exodeoxyribonuclease X -
K9F31_RS09590 (K9F31_09585) 1945815..1946045 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K9F31_RS09595 (K9F31_09590) 1946158..1946532 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K9F31_RS09600 (K9F31_09595) 1946536..1947405 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
K9F31_RS09605 (K9F31_09600) 1947422..1947760 + 339 WP_002911404.1 YebY family protein -
- 1947883..1948028 - 146 - - Antitoxin
- 1947919..1948021 + 103 - - Toxin
K9F31_RS09610 (K9F31_09605) 1948397..1948540 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K9F31_RS09615 (K9F31_09610) 1948645..1949613 - 969 WP_073971755.1 VirK/YbjX family protein -
K9F31_RS09620 (K9F31_09615) 1949770..1950423 + 654 WP_032441330.1 protein-serine/threonine phosphatase -
K9F31_RS09625 (K9F31_09620) 1950420..1950611 - 192 WP_002911395.1 YebW family protein -
K9F31_RS09630 (K9F31_09625) 1950709..1950948 - 240 WP_002911393.1 YebV family protein -
K9F31_RS09635 (K9F31_09630) 1951064..1952497 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T215820 NZ_CP082995:1947919-1948021 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT215820 NZ_CP082995:c1948028-1947883 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References