Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2016831..2016976 Replicon chromosome
Accession NZ_CP082988
Organism Klebsiella pneumoniae strain 7008.20

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2016867..2016969 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2016831..2016976 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9F32_RS09760 2011961..2014021 + 2061 WP_004151449.1 oligopeptidase B -
K9F32_RS09765 2014025..2014684 - 660 WP_038431281.1 exodeoxyribonuclease X -
K9F32_RS09770 2014763..2014993 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K9F32_RS09775 2015106..2015480 + 375 WP_039819395.1 CopC domain-containing protein YobA -
K9F32_RS09780 2015484..2016353 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
K9F32_RS09785 2016370..2016708 + 339 WP_002911404.1 YebY family protein -
- 2016831..2016976 - 146 - - Antitoxin
- 2016867..2016969 + 103 - - Toxin
K9F32_RS09790 2017345..2017488 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
K9F32_RS09795 2017593..2018561 - 969 WP_014907334.1 VirK/YbjX family protein -
K9F32_RS09800 2018718..2019371 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
K9F32_RS09805 2019368..2019559 - 192 WP_002911395.1 YebW family protein -
K9F32_RS09810 2019657..2019896 - 240 WP_002911393.1 YebV family protein -
K9F32_RS09815 2020012..2021445 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T215799 NZ_CP082988:2016867-2016969 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT215799 NZ_CP082988:c2016976-2016831 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References