Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 292895..294624 Replicon chromosome
Accession NC_008027
Organism Pseudomonas entomophila L48

Toxin (Protein)


Gene name pmenT Uniprot ID Q1IGF9
Locus tag PSEEN_RS01270 Protein ID WP_011531703.1
Coordinates 292895..293536 (+) Length 214 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID Q1IGF8
Locus tag PSEEN_RS01275 Protein ID WP_011531704.1
Coordinates 293536..294624 (+) Length 363 a.a.

Genomic Context

PSEEN_RS01260PSEEN_RS01265PSEEN_RS01270PSEEN_RS01275PSEEN_RS01285PSEEN_RS01255PSEEN_RS01280
Location: 291171..292226 (1056 bp)
Type: Others
Protein ID: WP_162042905.1
Location: 292317..292898 (582 bp)
Type: Others
Protein ID: WP_011531702.1
Location: 292895..293536 (642 bp)
Type: Toxin
Protein ID: WP_011531703.1
Location: 293536..294624 (1089 bp)
Type: Antitoxin
Protein ID: WP_011531704.1
Location: 296841..298514 (1674 bp)
Type: Others
Protein ID: WP_044487557.1
Location: 289532..290923 (1392 bp)
Type: Others
Protein ID: WP_011531700.1
Location: 294683..296524 (1842 bp)
Type: Others
Protein ID: WP_011531705.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PSEEN_RS01255289532..290923-1392WP_011531700.1L-cystine transporter-
PSEEN_RS01260291171..292226+1056WP_162042905.1haloacid dehalogenase-like hydrolase-
PSEEN_RS01265292317..292898+582WP_011531702.1DUF4433 domain-containing protein-
PSEEN_RS01270292895..293536+642WP_011531703.1DUF4433 domain-containing proteinToxin
PSEEN_RS01275293536..294624+1089WP_011531704.1macro domain-containing proteinAntitoxin
PSEEN_RS01280294683..296524-1842WP_011531705.1dihydroxy-acid dehydratase-
PSEEN_RS01285296841..298514+1674WP_044487557.1DUF4153 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 214 a.a.        Molecular weight: 24553.06 Da        Isoelectric Point: 9.1953

>T21578 WP_011531703.1 NC_008027:292895-293536 [Pseudomonas entomophila L48]
MTYTRLNPSKALIWRVVHRDNLPWLLDNGLCAVSRGNLSSGYVGIGNPDLISKRSRRAVPIHPGGTLADYVPFYFTPFSV
MMKNIHSGRGVQQRRNEEIVILVSSLYHVRSLGLPFVFTDAHAYPDWAGYYSDLEHLDKIDWQILQSRDFKRDPDDPRKM
ERYQAEALIHGHVPVAGLLGIVCYNEALQRRVDQEVRQRQLDLPVHARPGWYF

Download         Length: 642 bp

>T21578 NC_008027:292895-293536 [Pseudomonas entomophila L48]
ATGACGTATACCAGACTTAACCCAAGCAAAGCCCTGATCTGGCGAGTCGTCCACCGCGATAACCTCCCGTGGCTACTGGA
CAACGGCTTGTGTGCGGTTTCCAGAGGGAACCTCTCCAGCGGCTACGTCGGAATTGGTAATCCTGACTTGATCAGCAAGC
GTTCCAGGCGAGCGGTGCCCATCCATCCCGGTGGGACGCTGGCAGACTACGTGCCGTTCTACTTCACACCGTTCTCCGTG
ATGATGAAAAACATCCATTCAGGACGGGGAGTACAGCAACGTCGGAACGAGGAGATCGTGATTCTTGTCTCCAGCCTGTA
CCATGTGCGGTCCCTGGGGCTGCCCTTTGTCTTTACTGATGCTCATGCGTATCCGGACTGGGCAGGCTACTACAGCGACC
TGGAGCATCTGGACAAGATCGACTGGCAGATCTTGCAGTCCAGAGATTTCAAGCGTGACCCAGACGATCCACGAAAAATG
GAGCGCTATCAGGCTGAAGCCCTGATCCACGGGCACGTTCCAGTCGCTGGCCTTCTAGGGATTGTCTGCTACAACGAAGC
TTTGCAACGTCGTGTTGATCAGGAGGTCCGGCAACGTCAGCTGGATCTTCCCGTGCATGCTCGACCTGGGTGGTATTTCT
GA

Antitoxin


Download         Length: 363 a.a.        Molecular weight: 40495.36 Da        Isoelectric Point: 5.6423

>AT21578 WP_011531704.1 NC_008027:293536-294624 [Pseudomonas entomophila L48]
MIRFTQGNLLEAKAEALVNTVNTVGVMGKGIALMFKERFVENYRLYAAACKADEVVTGKMFITEVRELDGPRWVVNFPTK
RHWRSPSQLAWITDGLHDLRSFILANDVSSIAIPPLGAGNGGLPWAAVREQIEVVLGDLDADVLVFEPTSKYQNVSKRTG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERSIERFTPDDNPLNLQFSAHKYGPYTNRLEHLLNNLDGSYLH
CDKRIGDAGPLDVIWFDEGRKAFVDTYLHSEAKVHLPALEFTAELIDGFESPFGMELLATVDWMLHRDGVAPTVDAIREG
LQNWSGGKEAAARKNALFDDDSLATALKKLSVFQAQGVVQVH

Download         Length: 1089 bp

>AT21578 NC_008027:293536-294624 [Pseudomonas entomophila L48]
ATGATTCGCTTTACGCAAGGTAACCTGCTGGAGGCCAAGGCCGAAGCGCTGGTTAACACAGTCAACACCGTTGGGGTGAT
GGGTAAAGGCATTGCGCTGATGTTCAAAGAGCGCTTTGTAGAGAACTATCGCCTGTATGCGGCTGCCTGCAAAGCGGACG
AAGTTGTCACTGGAAAGATGTTCATCACCGAGGTTCGTGAGCTGGACGGCCCGCGCTGGGTTGTGAACTTTCCGACCAAG
CGTCATTGGCGTTCTCCATCACAGCTTGCCTGGATCACAGATGGCCTTCATGACTTGCGGAGCTTCATTCTTGCCAATGA
CGTGAGTTCCATAGCAATCCCTCCACTGGGGGCGGGTAATGGCGGGTTGCCTTGGGCTGCTGTGCGCGAACAGATTGAAG
TGGTGCTGGGGGATCTGGATGCTGACGTGCTCGTATTTGAGCCCACGAGCAAGTATCAAAATGTCTCGAAGCGCACAGGG
GTCGAGAAGCTTACCCCTGCCAGAGCGCTCATAGCCGAGCTGGTGCGTCGTTATTGGGTACTTGGTATGGAGTGCAGCTT
GCTGGAGATCCAGAAGCTGGCGTGGTTCCTGGAGCGCTCAATCGAGCGCTTCACTCCTGATGACAACCCGCTCAACCTGC
AGTTCAGTGCTCACAAGTACGGTCCTTACACTAACCGACTGGAGCATCTACTGAATAATCTCGATGGTAGTTATCTCCAT
TGTGACAAGCGTATCGGTGATGCTGGCCCCTTGGATGTGATCTGGTTCGATGAGGGGCGGAAGGCTTTCGTTGATACTTA
CTTGCACAGTGAGGCTAAGGTCCATTTACCTGCGTTGGAGTTTACGGCTGAGCTGATTGATGGCTTTGAGTCTCCATTTG
GTATGGAGCTTCTGGCCACGGTTGACTGGATGCTTCATCGGGATGGGGTGGCACCAACGGTCGATGCTATTCGGGAAGGG
TTGCAAAATTGGTCAGGTGGGAAGGAAGCAGCTGCCCGTAAGAATGCCCTCTTCGATGACGACTCTTTGGCAACTGCACT
AAAAAAGCTCTCGGTTTTCCAGGCTCAAGGCGTAGTGCAAGTACATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBQ1IGF9

Antitoxin

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Source
ID
Structure
AlphaFold DBQ1IGF8

References