Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2131386..2131531 Replicon chromosome
Accession NZ_CP082978
Organism Klebsiella pneumoniae strain BD-13

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2131422..2131524 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2131386..2131531 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9F21_RS10675 2126516..2128576 + 2061 WP_004151449.1 oligopeptidase B -
K9F21_RS10680 2128580..2129239 - 660 WP_002911407.1 exodeoxyribonuclease X -
K9F21_RS10685 2129318..2129548 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K9F21_RS10690 2129661..2130035 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K9F21_RS10695 2130039..2130908 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
K9F21_RS10700 2130925..2131263 + 339 WP_002911404.1 YebY family protein -
- 2131386..2131531 - 146 - - Antitoxin
- 2131422..2131524 + 103 - - Toxin
K9F21_RS10705 2131899..2132042 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K9F21_RS10710 2132147..2133115 - 969 WP_004151446.1 VirK/YbjX family protein -
K9F21_RS10715 2133272..2133925 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
K9F21_RS10720 2133922..2134113 - 192 WP_002911395.1 YebW family protein -
K9F21_RS10725 2134211..2134450 - 240 WP_002911393.1 YebV family protein -
K9F21_RS10730 2134566..2135999 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T215759 NZ_CP082978:2131422-2131524 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT215759 NZ_CP082978:c2131531-2131386 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References