Detailed information of TA system TA215682

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 549220..549873
• Replicon: chromosome
• Accession: NZ_CP082952
• Organism: Acinetobacter baumannii strain Cl300

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: A0A9E9PBS3
• Locus tag: K9C16_RS02655
• Protein ID: WP_002096593.1
• Coordinates: 549484..549873 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A2G8V6F0
• Locus tag: K9C16_RS02650
• Protein ID: WP_029424136.1
• Coordinates: 549220..549477 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K9C16_RS02630 (K9C16_02635)	544736..545743	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
K9C16_RS02635 (K9C16_02640)	545762..546139	+	378	WP_001216380.1	50S ribosomal protein L17	-
K9C16_RS02640 (K9C16_02645)	546321..547811	+	1491	WP_000415132.1	NAD(P)/FAD-dependent oxidoreductase	-
K9C16_RS02645 (K9C16_02650)	547860..549032	-	1173	WP_001190550.1	acyl-CoA dehydrogenase family protein	-
K9C16_RS02650 (K9C16_02655)	549220..549477	+	258	WP_029424136.1	succinate dehydrogenase assembly factor 2	Antitoxin
K9C16_RS02655 (K9C16_02660)	549484..549873	+	390	WP_002096593.1	hypothetical protein	Toxin
K9C16_RS02660 (K9C16_02665)	550643..551728	+	1086	WP_000049106.1	hypothetical protein	-
K9C16_RS02665 (K9C16_02670)	551806..552372	+	567	WP_000651536.1	rhombosortase	-
K9C16_RS02670 (K9C16_02675)	552560..554755	+	2196	WP_001158905.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-80)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15677.99 Da
• Isoelectric Point: 10.3890

>T215682 WP_002096593.1 NZ_CP082952:549484-549873 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T215682 NZ_CP110887:c4877452-4877075 [Dickeya solani]
ATGAAATGGGTGAGTGCGCAGGACGTCATTGACTTCCATGATCGTATTTTGCAGGTGTTGCCTGGTGTGGTGGGTATGGC
TGATCCGGGTCGGGCTGAGGAGTTGATTTATCGAGTACAAAACCGTCTTTATTATGAAGGTGTGACCGAACTGTTTGAGT
TGGCGGCGACGTATTGGGTAACTATTGCTCGTGGTCATATTTTTAATGATGGCAATAAACGCACTGCTTTTTTTGTTACC
ATGACATTTTTGCGCCGCAATGGCATATTGATTGTCGATAACGATAATTCGCTGGAAGAACTCACCATTAAGGCGGCAAC
CGGAGAATGCCTGGTGTCGGAACTCGCCGAACAATTAAGACAACGGGTGGAAAAATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10360.85 Da
• Isoelectric Point: 4.4909

>AT215682 WP_029424136.1 NZ_CP082952:549220-549477 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADLAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
YYVHG

Nucleotide

• Length: 258 bp

>AT215682 NZ_CP110887:c4877670-4877449 [Dickeya solani]
ATGAAGACTTATACCATTACTGAAGCCCGGCAAAATATTGCGACAGTCATTGATACGGCGGCCAGCGGTGAGCCGGTAGA
GATTAAGCGTCGGGATGGCACCTCGGCTGTACTCATCCCCAAAGCAGAGTTTGAGGCTTATCAGAAAGCCAGATTAGACG
CTGAATTCGATTTCATCATGCAGCGCCACGGACACACAATCAAAGCGCTCGCCGACAGATGA

Structures

Antitoxin

• AlphaFold DB: A0A2G8V6F0