Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 689715..689860 Replicon chromosome
Accession NZ_CP082936
Organism Klebsiella pneumoniae strain NDM-71

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 689751..689853 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 689715..689860 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8M01_RS03125 684845..686905 + 2061 WP_004151449.1 oligopeptidase B -
K8M01_RS03130 686909..687568 - 660 WP_021440386.1 exodeoxyribonuclease X -
K8M01_RS03135 687647..687877 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K8M01_RS03140 687990..688364 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K8M01_RS03145 688368..689237 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
K8M01_RS03150 689254..689592 + 339 WP_002911404.1 YebY family protein -
- 689715..689860 - 146 - - Antitoxin
- 689751..689853 + 103 - - Toxin
K8M01_RS03155 690228..690371 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K8M01_RS03160 690476..691444 - 969 WP_004151446.1 VirK/YbjX family protein -
K8M01_RS03165 691601..692254 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
K8M01_RS03170 692251..692442 - 192 WP_002911395.1 YebW family protein -
K8M01_RS03175 692540..692779 - 240 WP_002911393.1 YebV family protein -
K8M01_RS03180 692895..694328 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T215656 NZ_CP082936:689751-689853 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT215656 NZ_CP082936:c689860-689715 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References