Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1348358..1348886 Replicon chromosome
Accession NC_007969
Organism Psychrobacter cryohalolentis K5

Toxin (Protein)


Gene name relE Uniprot ID Q1QBQ3
Locus tag PCRYO_RS05755 Protein ID WP_010198775.1
Coordinates 1348358..1348645 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q1QBQ2
Locus tag PCRYO_RS05760 Protein ID WP_011513456.1
Coordinates 1348635..1348886 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCRYO_RS05730 1343703..1344479 - 777 WP_198010346.1 Nif3-like dinuclear metal center hexameric protein -
PCRYO_RS05735 1344781..1346109 + 1329 WP_011513452.1 trypsin-like peptidase domain-containing protein -
PCRYO_RS05740 1346234..1346500 - 267 WP_011513453.1 2Fe-2S iron-sulfur cluster binding domain-containing protein -
PCRYO_RS05745 1346698..1347831 - 1134 WP_011513454.1 ribonucleotide-diphosphate reductase subunit beta -
PCRYO_RS05750 1347904..1348287 - 384 WP_011513455.1 hypothetical protein -
PCRYO_RS05755 1348358..1348645 - 288 WP_010198775.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
PCRYO_RS05760 1348635..1348886 - 252 WP_011513456.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PCRYO_RS05765 1349068..1349823 - 756 WP_192941317.1 DUF4145 domain-containing protein -
PCRYO_RS05770 1350026..1352302 - 2277 WP_011513458.1 ribonucleoside-diphosphate reductase subunit alpha -
PCRYO_RS05775 1352865..1353170 - 306 WP_188004056.1 DUF493 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-72)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11081.92 Da        Isoelectric Point: 10.5715

>T21565 WP_010198775.1 NC_007969:c1348645-1348358 [Psychrobacter cryohalolentis K5]
MTYNLEFHPLALKEWKKIAPNIQQQFKKKLQQRLSNPHVPASKLSGHTDTYKIKLRTVGYRLVYTVKDDVVVVYVLAVGK
RENNKVYDNLATRQP

Download         Length: 288 bp

>T21565 NC_007969:c1348645-1348358 [Psychrobacter cryohalolentis K5]
ATGACTTATAATCTTGAGTTTCATCCTTTAGCGTTAAAAGAGTGGAAAAAGATAGCGCCAAATATTCAGCAGCAGTTCAA
GAAAAAATTACAGCAGCGATTGTCAAACCCTCATGTGCCTGCGTCAAAACTATCGGGACATACGGATACTTATAAAATCA
AATTACGCACCGTAGGCTATCGTCTGGTATATACCGTAAAAGATGATGTGGTGGTAGTTTATGTATTAGCAGTAGGCAAA
AGAGAAAACAACAAAGTATATGACAATCTTGCGACACGCCAGCCATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9066.40 Da        Isoelectric Point: 4.4278

>AT21565 WP_011513456.1 NC_007969:c1348886-1348635 [Psychrobacter cryohalolentis K5]
MKPIFATQTASISELKSNPSALIKQSDGESIAILNHNKPVAYLVSTDVFERMMEAMDDMALSQTVSARLNDGQIPIKVTL
DDL

Download         Length: 252 bp

>AT21565 NC_007969:c1348886-1348635 [Psychrobacter cryohalolentis K5]
ATGAAACCAATATTTGCGACACAGACAGCCAGTATCTCAGAACTAAAATCCAACCCGTCGGCACTGATTAAACAGTCAGA
CGGTGAGTCTATTGCTATTTTAAACCACAATAAACCCGTGGCTTACCTAGTTTCGACAGACGTATTCGAGCGCATGATGG
AAGCCATGGACGACATGGCATTAAGCCAAACCGTTAGCGCACGGTTAAATGACGGGCAGATACCGATAAAGGTAACGTTG
GATGACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0Q9ZX66

Antitoxin

Source ID Structure
AlphaFold DB Q1QBQ2

References