Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1348358..1348886 Replicon chromosome
Accession NC_007969
Organism Psychrobacter cryohalolentis K5

Toxin (Protein)


Gene name relE Uniprot ID Q1QBQ3
Locus tag PCRYO_RS05755 Protein ID WP_010198775.1
Coordinates 1348358..1348645 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q1QBQ2
Locus tag PCRYO_RS05760 Protein ID WP_011513456.1
Coordinates 1348635..1348886 (-) Length 84 a.a.

Genomic Context

PCRYO_RS05735PCRYO_RS05730PCRYO_RS05740PCRYO_RS05745PCRYO_RS05750PCRYO_RS05755PCRYO_RS05760PCRYO_RS05765PCRYO_RS05770PCRYO_RS05775
Location: 1344781..1346109 (1329 bp)
Type: Others
Protein ID: WP_011513452.1
Location: 1343703..1344479 (777 bp)
Type: Others
Protein ID: WP_198010346.1
Location: 1346234..1346500 (267 bp)
Type: Others
Protein ID: WP_011513453.1
Location: 1346698..1347831 (1134 bp)
Type: Others
Protein ID: WP_011513454.1
Location: 1347904..1348287 (384 bp)
Type: Others
Protein ID: WP_011513455.1
Location: 1348358..1348645 (288 bp)
Type: Toxin
Protein ID: WP_010198775.1
Location: 1348635..1348886 (252 bp)
Type: Antitoxin
Protein ID: WP_011513456.1
Location: 1349068..1349823 (756 bp)
Type: Others
Protein ID: WP_192941317.1
Location: 1350026..1352302 (2277 bp)
Type: Others
Protein ID: WP_011513458.1
Location: 1352865..1353170 (306 bp)
Type: Others
Protein ID: WP_188004056.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PCRYO_RS057301343703..1344479-777WP_198010346.1Nif3-like dinuclear metal center hexameric protein-
PCRYO_RS057351344781..1346109+1329WP_011513452.1trypsin-like peptidase domain-containing protein-
PCRYO_RS057401346234..1346500-267WP_011513453.12Fe-2S iron-sulfur cluster binding domain-containing protein-
PCRYO_RS057451346698..1347831-1134WP_011513454.1ribonucleotide-diphosphate reductase subunit beta-
PCRYO_RS057501347904..1348287-384WP_011513455.1hypothetical protein-
PCRYO_RS057551348358..1348645-288WP_010198775.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE familyToxin
PCRYO_RS057601348635..1348886-252WP_011513456.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
PCRYO_RS057651349068..1349823-756WP_192941317.1DUF4145 domain-containing protein-
PCRYO_RS057701350026..1352302-2277WP_011513458.1ribonucleoside-diphosphate reductase subunit alpha-
PCRYO_RS057751352865..1353170-306WP_188004056.1DUF493 domain-containing protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-72)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11081.92 Da        Isoelectric Point: 10.5715

>T21565 WP_010198775.1 NC_007969:c1348645-1348358 [Psychrobacter cryohalolentis K5]
MTYNLEFHPLALKEWKKIAPNIQQQFKKKLQQRLSNPHVPASKLSGHTDTYKIKLRTVGYRLVYTVKDDVVVVYVLAVGK
RENNKVYDNLATRQP

Download         Length: 288 bp

>T21565 NC_007969:c1348645-1348358 [Psychrobacter cryohalolentis K5]
ATGACTTATAATCTTGAGTTTCATCCTTTAGCGTTAAAAGAGTGGAAAAAGATAGCGCCAAATATTCAGCAGCAGTTCAA
GAAAAAATTACAGCAGCGATTGTCAAACCCTCATGTGCCTGCGTCAAAACTATCGGGACATACGGATACTTATAAAATCA
AATTACGCACCGTAGGCTATCGTCTGGTATATACCGTAAAAGATGATGTGGTGGTAGTTTATGTATTAGCAGTAGGCAAA
AGAGAAAACAACAAAGTATATGACAATCTTGCGACACGCCAGCCATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9066.40 Da        Isoelectric Point: 4.4278

>AT21565 WP_011513456.1 NC_007969:c1348886-1348635 [Psychrobacter cryohalolentis K5]
MKPIFATQTASISELKSNPSALIKQSDGESIAILNHNKPVAYLVSTDVFERMMEAMDDMALSQTVSARLNDGQIPIKVTL
DDL

Download         Length: 252 bp

>AT21565 NC_007969:c1348886-1348635 [Psychrobacter cryohalolentis K5]
ATGAAACCAATATTTGCGACACAGACAGCCAGTATCTCAGAACTAAAATCCAACCCGTCGGCACTGATTAAACAGTCAGA
CGGTGAGTCTATTGCTATTTTAAACCACAATAAACCCGTGGCTTACCTAGTTTCGACAGACGTATTCGAGCGCATGATGG
AAGCCATGGACGACATGGCATTAAGCCAAACCGTTAGCGCACGGTTAAATGACGGGCAGATACCGATAAAGGTAACGTTG
GATGACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A0Q9ZX66

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBQ1QBQ2

References