Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) brnT-relB/BrnT-RelB
Location 24275..24615 Replicon plasmid 1
Accession NC_007968
Organism Psychrobacter cryohalolentis K5

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag PCRYO_RS13125 Protein ID WP_011512349.1
Coordinates 24275..24418 (-) Length 48 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7W2MYR8
Locus tag PCRYO_RS12880 Protein ID WP_011512369.1
Coordinates 24415..24615 (-) Length 67 a.a.

Genomic Context

PCRYO_RS12845PCRYO_RS12850PCRYO_RS12855PCRYO_RS12860PCRYO_RS12865PCRYO_RS12895PCRYO_RS12900PCRYO_RS12905PCRYO_RS12870PCRYO_RS13125PCRYO_RS12880PCRYO_RS12885PCRYO_RS12890
Location: 19461..20270 (810 bp)
Type: Others
Protein ID: WP_011512343.1
Location: 20480..21115 (636 bp)
Type: Others
Protein ID: WP_011512344.1
Location: 21128..21331 (204 bp)
Type: Others
Protein ID: WP_041753792.1
Location: 21589..22599 (1011 bp)
Type: Others
Protein ID: WP_011512346.1
Location: 22605..23591 (987 bp)
Type: Others
Protein ID: WP_011512347.1
Location: 25908..26282 (375 bp)
Type: Others
Protein ID: WP_011512351.1
Location: 26924..27871 (948 bp)
Type: Others
Protein ID: WP_011512352.1
Location: 28031..29158 (1128 bp)
Type: Others
Protein ID: WP_011512353.1
Location: 23751..24047 (297 bp)
Type: Others
Protein ID: WP_041753794.1
Location: 24275..24418 (144 bp)
Type: Toxin
Protein ID: WP_011512349.1
Location: 24415..24615 (201 bp)
Type: Antitoxin
Protein ID: WP_011512369.1
Location: 24717..24977 (261 bp)
Type: Others
Protein ID: WP_011512370.1
Location: 25045..25446 (402 bp)
Type: Others
Protein ID: WP_011512350.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PCRYO_RS1284519461..20270+810WP_011512343.1hypothetical protein-
PCRYO_RS1285020480..21115+636WP_011512344.1AAA family ATPase-
PCRYO_RS1285521128..21331+204WP_041753792.1hypothetical protein-
PCRYO_RS1286021589..22599+1011WP_011512346.1AAA family ATPase-
PCRYO_RS1286522605..23591+987WP_011512347.1DUF4435 domain-containing protein-
PCRYO_RS1287023751..24047-297WP_041753794.1hypothetical protein-
PCRYO_RS1312524275..24418-144WP_011512349.1BrnT family toxinToxin
PCRYO_RS1288024415..24615-201WP_011512369.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
PCRYO_RS1288524717..24977-261WP_011512370.1hypothetical protein-
PCRYO_RS1289025045..25446-402WP_011512350.1hypothetical protein-
PCRYO_RS1289525908..26282+375WP_011512351.1hypothetical protein-
PCRYO_RS1290026924..27871+948WP_011512352.1replication initiation protein RepM-
PCRYO_RS1290528031..29158+1128WP_011512353.1DUF262 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..4122141221


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-47)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-54)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5780.34 Da        Isoelectric Point: 4.4963

>T21564 WP_011512349.1 NC_007968:c24418-24275 [Psychrobacter cryohalolentis K5]
MIEFEWDEQKNSSNQRKHGLCFEEAARVFFDPLCLRQQDRYENGEER

Download         Length: 144 bp

>T21564 NC_007968:c24418-24275 [Psychrobacter cryohalolentis K5]
ATGATTGAATTTGAATGGGATGAACAGAAAAATAGCAGTAATCAACGCAAACATGGCTTATGCTTTGAAGAAGCAGCTCG
GGTATTTTTTGATCCTTTGTGTTTGCGTCAACAAGACCGATATGAAAACGGTGAAGAGCGGTAG

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7427.25 Da        Isoelectric Point: 4.1313

>AT21564 WP_011512369.1 NC_007968:c24615-24415 [Psychrobacter cryohalolentis K5]
MSTTNYNIRLDQELKDKAFSVLEGYGLTPSQAIKLFLHQVAETNSIPLSFDYQTMPSTNTLEDGDQ

Download         Length: 201 bp

>AT21564 NC_007968:c24615-24415 [Psychrobacter cryohalolentis K5]
ATGAGCACAACCAATTATAATATCCGTCTCGATCAAGAATTAAAAGACAAGGCGTTTTCGGTGCTTGAAGGCTATGGTTT
AACGCCTTCTCAGGCGATTAAGTTATTTTTGCATCAGGTAGCAGAAACCAATAGCATACCGCTGTCTTTTGATTACCAGA
CAATGCCTAGTACCAATACGCTTGAAGACGGTGATCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A7W2MYR8

References