Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 4188166..4188698 Replicon chromosome
Accession NZ_CP082926
Organism Shewanella inventionis strain D1489

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag K8B83_RS18705 Protein ID WP_188740132.1
Coordinates 4188405..4188698 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag K8B83_RS18700 Protein ID WP_188740131.1
Coordinates 4188166..4188405 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8B83_RS18675 (K8B83_18570) 4183421..4183969 - 549 WP_188740126.1 cupin domain-containing protein -
K8B83_RS18680 (K8B83_18575) 4184200..4185507 + 1308 WP_223418650.1 FAD-binding oxidoreductase -
K8B83_RS18685 (K8B83_18580) 4186561..4186719 - 159 WP_188740128.1 hypothetical protein -
K8B83_RS18690 (K8B83_18585) 4187052..4187231 - 180 WP_188740129.1 hypothetical protein -
K8B83_RS18695 (K8B83_18590) 4187592..4187999 - 408 WP_188740130.1 GFA family protein -
K8B83_RS18700 (K8B83_18595) 4188166..4188405 + 240 WP_188740131.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
K8B83_RS18705 (K8B83_18600) 4188405..4188698 + 294 WP_188740132.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K8B83_RS18710 (K8B83_18605) 4188778..4189671 - 894 WP_188740133.1 NAD(P)-dependent oxidoreductase -
K8B83_RS18715 (K8B83_18610) 4189810..4190046 - 237 WP_188740144.1 hypothetical protein -
K8B83_RS18720 (K8B83_18615) 4190254..4191966 - 1713 WP_188740134.1 amidase -
K8B83_RS18725 (K8B83_18620) 4192045..4193157 - 1113 WP_188740135.1 agmatine deiminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-77)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11271.99 Da        Isoelectric Point: 9.6110

>T215624 WP_188740132.1 NZ_CP082926:4188405-4188698 [Shewanella inventionis]
MSKFELSGKAKSDLIKVAKYTQLTWGTAQRNDYLKLLDNTFHQLADEPMLGVNCDYISEGYRKQPQGSHIIYYKEHKTNQ
ILIVRILHKSMDVNRAL

Download         Length: 294 bp

>T215624 NZ_CP110859:649115-649429 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8869.73 Da        Isoelectric Point: 4.3843

>AT215624 WP_188740131.1 NZ_CP082926:4188166-4188405 [Shewanella inventionis]
MAKNTSVTLGEHFDQFINQQLKSGRYGSASEVVRAGLRVLEDQETKIMNLRNMLTEGENSGVTDYSYDSLISELDQDSH

Download         Length: 240 bp

>AT215624 NZ_CP110859:649426-649842 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References