Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 1089457..1090006 Replicon chromosome
Accession NZ_CP082926
Organism Shewanella inventionis strain D1489

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag K8B83_RS04975 Protein ID WP_188736147.1
Coordinates 1089457..1089756 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag K8B83_RS04980 Protein ID WP_188736149.1
Coordinates 1089764..1090006 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8B83_RS04945 (K8B83_04905) 1085066..1085500 - 435 WP_188736137.1 cytidine/deoxycytidylate deaminase family protein -
K8B83_RS04950 (K8B83_04910) 1085607..1086572 - 966 WP_188736139.1 LysR family transcriptional regulator -
K8B83_RS04955 (K8B83_04915) 1086909..1087667 + 759 WP_188736514.1 DUF4437 domain-containing protein -
K8B83_RS04960 (K8B83_04920) 1088235..1088579 + 345 WP_188736141.1 type II toxin-antitoxin system RelE/ParE family toxin -
K8B83_RS04965 (K8B83_04925) 1088581..1088856 + 276 WP_188736143.1 helix-turn-helix transcriptional regulator -
K8B83_RS04970 (K8B83_04930) 1089021..1089260 + 240 WP_188736145.1 hypothetical protein -
K8B83_RS04975 (K8B83_04935) 1089457..1089756 - 300 WP_188736147.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K8B83_RS04980 (K8B83_04940) 1089764..1090006 - 243 WP_188736149.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
K8B83_RS04985 (K8B83_04945) 1090842..1092776 - 1935 WP_188736151.1 B12-binding domain-containing radical SAM protein -
K8B83_RS04990 (K8B83_04950) 1092846..1093166 - 321 WP_188736153.1 helix-turn-helix transcriptional regulator -
K8B83_RS04995 (K8B83_04955) 1093163..1094488 - 1326 WP_188736155.1 HipA domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-54)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11587.18 Da        Isoelectric Point: 9.2734

>T215618 WP_188736147.1 NZ_CP082926:c1089756-1089457 [Shewanella inventionis]
MQKNKYKLSNLAQYHLRKVKNYTVENFSELQWHNYKDSLLSGFQMLADNPGFGRSCDDIYPNGFYFPIGKHTAYFTKEHD
FILVVAVLGQSQLPQNHLK

Download         Length: 300 bp

>T215618 NZ_CP110857:2858622-2858801 [Enterobacter hormaechei]
ATGGATAGCAGGAATGCAATAGCAATGATAGAAGCCGATGGGTGGTATCTGGTGAGAGTTAAAGGCAGTCATCACCAGTT
CAAACACCCAACGAAAAAGGGGCTGGTAACGGTAAAGCATCCACAGAAAGACATACCGTTACCAACACTGAAAAGCATCA
AAAAACAGGCGGGGCTCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9107.37 Da        Isoelectric Point: 5.7052

>AT215618 WP_188736149.1 NZ_CP082926:c1090006-1089764 [Shewanella inventionis]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDTVVVMSMRDFEELEAMKVEYLKHCFKSAKEDLDNKNAVDGESFLNSL

Download         Length: 243 bp

>AT215618 NZ_CP110857:2858823-2859227 [Enterobacter hormaechei]
ATGTTGTACCCTGTTGCTATTGATAAAGGCGATTCATCCTTCGGCGTTCGCGTACCTGATATTCCTGGCTGCTTCTCTGG
CGGTGAAGATTATCAGGACGCGATCGAAAGCGTACGTGAAGCGATCGAGGCACACATCGAATTACTGGTTGAAGATGGCG
AGAGCGTTCCCGAAGCAACGACCGTCGAAAACTGGCTATCTGATCCGGAGTACGCCGGTGCGGTATGGGCCCTAGTTGAC
GTGGATATAACACGCCTGATGGGAAAAGCGGAAAAAATCAATGTGACGCTACCCTCATTACTGATCCGACGTATTGATCA
GTTTGTGGCCGCGCATCCTGAATATGGAAGCCGTTCGGGCTTCCTTTCTCGCGTCGCTGCTGACAAGGTTATTAATCAAC
GATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References