21560

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3284952..3285358 Replicon chromosome
Accession NC_007963
Organism Chromohalobacter salexigens DSM 3043

Toxin (Protein)


Gene name EcnB Uniprot ID A0A317QVG6
Locus tag CSAL_RS17040 Protein ID WP_050934549.1
Coordinates 3285230..3285358 (-) Length 43 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q1QTB6
Locus tag CSAL_RS14900 Protein ID WP_011508238.1
Coordinates 3284952..3285083 (-) Length 44 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSAL_RS14875 3280373..3280684 - 312 WP_011508233.1 hypothetical protein -
CSAL_RS14880 3280833..3281765 + 933 WP_011508234.1 ABC transporter substrate-binding protein -
CSAL_RS14885 3281889..3282977 + 1089 WP_148266903.1 ABC transporter permease -
CSAL_RS14890 3282990..3284054 + 1065 WP_011508236.1 ABC transporter ATP-binding protein -
CSAL_RS14895 3284066..3284818 + 753 WP_043559726.1 ABC transporter permease -
CSAL_RS14900 3284952..3285083 - 132 WP_011508238.1 entericidin A/B family lipoprotein Antitoxin
CSAL_RS17040 3285230..3285358 - 129 WP_050934549.1 entericidin A/B family lipoprotein Toxin
CSAL_RS14905 3285466..3285894 + 429 WP_011508240.1 HIT family protein -
CSAL_RS14910 3285908..3286267 - 360 WP_011508241.1 hypothetical protein -
CSAL_RS14915 3286264..3286806 - 543 WP_043558635.1 hypothetical protein -
CSAL_RS14920 3287050..3288210 + 1161 WP_011508243.1 glycerate kinase -
CSAL_RS14925 3288376..3288849 + 474 WP_011508244.1 DNA starvation/stationary phase protection protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Membrane lipoprotein, lipid attachment site

(1-21)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 43 a.a.        Molecular weight: 4242.87 Da        Isoelectric Point: 4.2645

>T21560 WP_050934549.1 NC_007963:c3285358-3285230 [Chromohalobacter salexigens DSM 3043]
MKRTTVAILGLLLLVALSGCNTIQGAGEDIERGGEAVQDAAS

Download         Length: 129 bp

>T21560 NC_007963:c3285358-3285230 [Chromohalobacter salexigens DSM 3043]
ATGAAGCGTACAACGGTTGCGATCTTGGGTTTGCTGTTGCTGGTGGCGCTGAGTGGATGCAATACCATCCAGGGCGCGGG
TGAGGATATCGAGCGTGGCGGTGAAGCGGTTCAGGATGCCGCTTCCTGA

Antitoxin


Download         Length: 44 a.a.        Molecular weight: 4539.10 Da        Isoelectric Point: 3.6910

>AT21560 WP_011508238.1 NC_007963:c3285083-3284952 [Chromohalobacter salexigens DSM 3043]
MKRMLAFSLLLMFTAGAISGCNTFEGAGEDIEQGGEEVQEAAD

Download         Length: 132 bp

>AT21560 NC_007963:c3285083-3284952 [Chromohalobacter salexigens DSM 3043]
ATGAAACGGATGCTGGCTTTTTCCCTGCTGCTGATGTTCACCGCTGGCGCAATCAGCGGCTGCAACACTTTCGAGGGTGC
AGGTGAAGACATCGAGCAAGGCGGCGAAGAAGTGCAAGAAGCCGCAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A317QVG6

Antitoxin

Source ID Structure
AlphaFold DB A0A285VK24

References