Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-RelB
Location 5245410..5245942 Replicon chromosome
Accession NZ_CP082909
Organism Endozoicomonas sp. 4G

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag K7B67_RS20770 Protein ID WP_252177761.1
Coordinates 5245673..5245942 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K7B67_RS20765 Protein ID WP_252177760.1
Coordinates 5245410..5245670 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7B67_RS20745 5240774..5241739 + 966 WP_252177756.1 glycine--tRNA ligase subunit alpha -
K7B67_RS20750 5241739..5243838 + 2100 WP_252177757.1 glycine--tRNA ligase subunit beta -
K7B67_RS20755 5243959..5244519 + 561 WP_252177758.1 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase -
K7B67_RS20760 5244536..5245261 + 726 WP_252177759.1 lysophospholipid acyltransferase family protein -
K7B67_RS20765 5245410..5245670 + 261 WP_252177760.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
K7B67_RS20770 5245673..5245942 + 270 WP_252177761.1 type II toxin-antitoxin system YafQ family toxin Toxin
K7B67_RS20775 5245956..5246531 - 576 WP_252177762.1 D-sedoheptulose 7-phosphate isomerase -
K7B67_RS20780 5246666..5249080 - 2415 WP_252177763.1 DNA topoisomerase (ATP-hydrolyzing) subunit B -
K7B67_RS20785 5249073..5250251 - 1179 WP_252177764.1 DNA replication/repair protein RecF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10695.52 Da        Isoelectric Point: 9.8461

>T215551 WP_252177761.1 NZ_CP082909:5245673-5245942 [Endozoicomonas sp. 4G]
MLVPVFLTRFDKDVKKAKKQGKDMEKLKFITRQLVEQKPLAPRYRDHLLTGNYNGRRECHIEPDWLLIYRLADDCIFFER
LGSHSELFK

Download         Length: 270 bp

>T215551 NZ_CP110814:c2370285-2370109 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9778.29 Da        Isoelectric Point: 4.7049

>AT215551 WP_252177760.1 NZ_CP082909:5245410-5245670 [Endozoicomonas sp. 4G]
MSKSAVVKARVEPELKKQAEAVFRKIGLNTTQAITLFYTQVELCNGLPFDVRIPNEETLKAFEESDRGEGLVKCEDLEDM
FKKLEL

Download         Length: 261 bp

>AT215551 NZ_CP110814:c2370063-2369647 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCACGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References