Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 5237920..5238588 Replicon chromosome
Accession NZ_CP082909
Organism Endozoicomonas sp. 4G

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag K7B67_RS20730 Protein ID WP_252177753.1
Coordinates 5237920..5238336 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag K7B67_RS20735 Protein ID WP_252177754.1
Coordinates 5238337..5238588 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7B67_RS20710 5233658..5234167 + 510 WP_252177749.1 peptide deformylase -
K7B67_RS20715 5234284..5235249 + 966 WP_252177750.1 methionyl-tRNA formyltransferase -
K7B67_RS20720 5235249..5236553 + 1305 WP_252177751.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
K7B67_RS20725 5236550..5237923 + 1374 WP_252177752.1 Trk system potassium transporter TrkA -
K7B67_RS20730 5237920..5238336 - 417 WP_252177753.1 type II toxin-antitoxin system VapC family toxin Toxin
K7B67_RS20735 5238337..5238588 - 252 WP_252177754.1 plasmid stabilization protein Antitoxin
K7B67_RS20740 5239103..5240551 + 1449 WP_252177755.1 TrkH family potassium uptake protein -
K7B67_RS20745 5240774..5241739 + 966 WP_252177756.1 glycine--tRNA ligase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15232.46 Da        Isoelectric Point: 4.8605

>T215550 WP_252177753.1 NZ_CP082909:c5238336-5237920 [Endozoicomonas sp. 4G]
MILLDTNIISETMRQSPDTAVVGWLNEQISETLYLSSVTLAELLFGILALPDGRRKQQLSQAVDQYTTLFRGRILEFDVA
AAREYAELAVLARKRGRGFPVPDGYIAAIASVHGFRVASRDVAPFEAANVPVVNPWLD

Download         Length: 417 bp

>T215550 NZ_CP110814:2287395-2288717 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9452.87 Da        Isoelectric Point: 4.6310

>AT215550 WP_252177754.1 NZ_CP082909:c5238588-5238337 [Endozoicomonas sp. 4G]
MAMMTLRNIPDELYSALKVRAKRNNRSMVAEVRNILREVLQPEDRVLMGDALVNAGQDIGLTDEEVDILEQNRDKTPAEP
VKF

Download         Length: 252 bp

>AT215550 NZ_CP110814:2287129-2287395 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References