Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 5084239..5084767 Replicon chromosome
Accession NZ_CP082909
Organism Endozoicomonas sp. 4G

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K7B67_RS20065 Protein ID WP_252177626.1
Coordinates 5084483..5084767 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K7B67_RS20060 Protein ID WP_252177625.1
Coordinates 5084239..5084493 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7B67_RS20035 5079506..5079832 + 327 WP_252177620.1 hypothetical protein -
K7B67_RS20040 5080709..5081518 + 810 WP_252177621.1 adenine-specific methyltransferase EcoRI family protein -
K7B67_RS20045 5081570..5082691 + 1122 WP_252177622.1 transposase -
K7B67_RS20050 5082713..5083051 + 339 WP_252177623.1 adenine-specific methyltransferase EcoRI family protein -
K7B67_RS20055 5083052..5084131 + 1080 WP_252177624.1 DUF262 domain-containing protein -
K7B67_RS20060 5084239..5084493 + 255 WP_252177625.1 antitoxin Antitoxin
K7B67_RS20065 5084483..5084767 + 285 WP_252177626.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K7B67_RS20070 5084888..5085751 - 864 WP_252177627.1 YicC/YloC family endoribonuclease -
K7B67_RS20075 5085914..5086633 + 720 WP_252177628.1 ribonuclease PH -
K7B67_RS20080 5086686..5087462 - 777 WP_252177629.1 exodeoxyribonuclease III -
K7B67_RS20085 5088049..5088693 + 645 WP_252177630.1 orotate phosphoribosyltransferase -
K7B67_RS20090 5088760..5089350 - 591 WP_252177631.1 nucleoid occlusion factor SlmA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 5081570..5082691 1121


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11570.54 Da        Isoelectric Point: 11.0269

>T215547 WP_252177626.1 NZ_CP082909:5084483-5084767 [Endozoicomonas sp. 4G]
MTYELIFKEEALKEWRQLDQSLRDQFRKKLDERRRSPKVQSARLRDIKNCYKIKLRSSGFRLVYEVRDKEIVIVVIAVGK
RDRQKVYREAQRRL

Download         Length: 285 bp

>T215547 NZ_CP110814:c1802778-1802404 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTATGGCCTCACACTGAATGACACACCTTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9379.75 Da        Isoelectric Point: 4.2942

>AT215547 WP_252177625.1 NZ_CP082909:5084239-5084493 [Endozoicomonas sp. 4G]
MPNVHPVLADMATSISEFKKNPMAVIHQGGGQPVAVLNRNEPAFYCVPSVVWEAVLDQLEDIELARLVEERKNQKEIPVD
LDDL

Download         Length: 255 bp

>AT215547 NZ_CP110814:c1803235-1802867 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGATTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References