Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 4437494..4438056 Replicon chromosome
Accession NZ_CP082909
Organism Endozoicomonas sp. 4G

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag K7B67_RS17390 Protein ID WP_252177141.1
Coordinates 4437742..4438056 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag K7B67_RS17385 Protein ID WP_252177140.1
Coordinates 4437494..4437742 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7B67_RS17370 4433236..4433706 - 471 WP_252177137.1 hypothetical protein -
K7B67_RS17375 4433799..4435367 - 1569 WP_252177138.1 hypothetical protein -
K7B67_RS17380 4435551..4437299 - 1749 WP_252177139.1 hypothetical protein -
K7B67_RS17385 4437494..4437742 + 249 WP_252177140.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
K7B67_RS17390 4437742..4438056 + 315 WP_252177141.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K7B67_RS17395 4438138..4438545 - 408 WP_252177142.1 type II restriction endonuclease -
K7B67_RS17400 4438656..4439531 + 876 WP_256484873.1 IS1634 family transposase -
K7B67_RS17405 4439593..4440015 - 423 WP_252177143.1 hypothetical protein -
K7B67_RS17410 4440250..4440642 + 393 WP_252177144.1 hypothetical protein -
K7B67_RS17415 4440694..4441734 + 1041 WP_252177145.1 IS66 family transposase -
K7B67_RS17420 4442203..4442451 + 249 WP_252177146.1 type II toxin-antitoxin system ParD family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-96)

Antitoxin

Antitoxin ParD

(3-64)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 12333.19 Da        Isoelectric Point: 10.0937

>T215545 WP_252177141.1 NZ_CP082909:4437742-4438056 [Endozoicomonas sp. 4G]
MLQKINRKVRVTPRARDDLRNIGRYTLRTWGKTQRNHYLKSIEARFHWLAENPQLGKYRADISEGYFSFPEGQHVIFYMI
GSNFIDIIGVLHKEMDVIGYFLEG

Download         Length: 315 bp

>T215545 NZ_CP110814:1790634-1790885 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9016.01 Da        Isoelectric Point: 4.4915

>AT215545 WP_252177140.1 NZ_CP082909:4437494-4437742 [Endozoicomonas sp. 4G]
MATTSLSLGEHWEVFIKNEISSGRYGSASEVVRDALRAMEERKSKLEALRSHLAEGATQAGKGEFINDFSMDSLINDLDA
EP

Download         Length: 249 bp

>AT215545 NZ_CP110814:1790882-1791136 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References