Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 3602278..3602810 Replicon chromosome
Accession NZ_CP082909
Organism Endozoicomonas sp. 4G

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K7B67_RS14110 Protein ID WP_252176530.1
Coordinates 3602541..3602810 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K7B67_RS14105 Protein ID WP_252176529.1
Coordinates 3602278..3602541 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7B67_RS14075 3597812..3598144 - 333 WP_252176524.1 type II toxin-antitoxin system HicB family antitoxin -
K7B67_RS14080 3598141..3598287 - 147 WP_256484867.1 type II toxin-antitoxin system HicA family toxin -
K7B67_RS14085 3598309..3599724 - 1416 WP_252176525.1 transposase -
K7B67_RS14090 3599795..3600247 + 453 WP_252176526.1 IS200/IS605 family transposase -
K7B67_RS14095 3600233..3600394 - 162 WP_252176527.1 hypothetical protein -
K7B67_RS14100 3600844..3601983 - 1140 WP_252176528.1 ISAs1 family transposase -
K7B67_RS14105 3602278..3602541 + 264 WP_252176529.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
K7B67_RS14110 3602541..3602810 + 270 WP_252176530.1 type II toxin-antitoxin system YafQ family toxin Toxin
K7B67_RS14115 3602891..3603796 - 906 WP_252176531.1 hypothetical protein -
K7B67_RS14120 3603933..3604583 - 651 WP_252176532.1 hypothetical protein -
K7B67_RS14125 3604759..3605106 + 348 WP_252176533.1 phage integrase N-terminal SAM-like domain-containing protein -
K7B67_RS14130 3605726..3606709 - 984 WP_252176534.1 transglutaminase-like domain-containing protein -
K7B67_RS14135 3606729..3607373 - 645 WP_252176535.1 HNH endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3591881..3608453 16572


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10736.61 Da        Isoelectric Point: 10.1462

>T215544 WP_252176530.1 NZ_CP082909:3602541-3602810 [Endozoicomonas sp. 4G]
MLTPVRSTKFKKDYKKVERQGKDLKKLKTIMVRLAKEEILEPKYKDHYLTGNYKGRRECHIEPDWLLIYMIVGSEIFFER
TGSHSELFR

Download         Length: 270 bp

>T215544 NZ_CP110814:c1119961-1118888 [Escherichia coli]
ATGACAATCAGGAGTTACAAAAACTTAAATCTGGTCAGGGCAAATATCGAGACTGAATCCAGACAATTCATTGAAAATAA
AAACTATTCAATCCAATCAATTGGTCCTATGCCAGGGTCAAGGGCTGGGCTTCGGGTCGTATTTACCAGACCAGGGGTTA
ACTTGGCAACTGTGGACATTTTTTATAACGGGGACGGTTCGACTACAATTCAATATCTCACTGGAGCCAATCGTTCTCTG
GGCCAAGAGTTAGCGGATCATCTTTTTGAAACCATCAATCCTGCTGAATTTGAGCAGGTAAATATGGTACTGCAAGGATT
TGTAGAGACAAGCGTTCTACCTGTACTTGAGCTATCAGCAGATGAATCGCATATAGAGTTCAGAGAACACTCTCGTAACG
CTCATACCGTAGTGTGGAAAATTATTTCCACCAGCTATCAGGACGAATTGACTGTGAGCCTGCATATCACAACAGGTAAG
CTCCAGATTCAGGGCCGACCGCTGTCATGTTACAGAGTTTTCACGTTTAACTTGGCAGCCCTGCTTGATTTACAGGGTTT
GGAGAAAGTGCTAATCCGCCAGGAGGATGGTAAAGCTAATATTGTTCAACAGGAGGTTGCCCGCACTTACTTGCAGACTG
TAATGGCCGATGCTTACCCGCATCTCCACGTGACTGCCGAAAAATTGCTCGTTTCAGGGCTATGTGTTAAACTCGCCGCC
CCTGATTTGCCTGACTACTGTATGTTACTTTATCCTGAACTACGCACCATTGAAGGTGTCTTAAAAAGTAAGATGAGTGG
GTTAGGCATGCCAGTACAGCAGCCGGCAGGTTTTGGAACTTACTTTGATAAACCTGCTGCTCATTACATTCTGAAACCGC
AATTTGCAGCTACTCTTAGACCGGAACAGATTAACATCATCAGCACAGCCTATACTTTTTTTAATGTGGAACGTCATTCT
CTGTTCCACATGGAAACTGTGGTCGATGCCAGCCGTATGATTTCTGATATGGCCCGGTTGATGGGTAAAGCCACTAGAGC
GTGGGGAATAATCAAGGACTTATATATTGTTTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9809.15 Da        Isoelectric Point: 4.5127

>AT215544 WP_252176529.1 NZ_CP082909:3602278-3602541 [Endozoicomonas sp. 4G]
MSKSAMIRARIEPDVKEHAEAIFRKLGLNATDAITLFYKQVGLCNGLPFDVRIPNEETLKAFKDTDKGVGLTHYDSMEEM
FDDLDAD

Download         Length: 264 bp

>AT215544 NZ_CP110814:c1118895-1118524 [Escherichia coli]
TTGTTTGAAATCACCGGAATTAACGTCTCAGGGGCTCTAAAAGCTGTCGTTATGGCGACCGGCTTCGAGAACCCTTTGTC
CTCAGTTAATGAAATTGAGACGAAACTTTCTGCCCTACTGGGTAGTGAGACCACTGGTGAAATCCTTTTTGACCTCTTGT
GCGCTAACGGTCCAGAGTGGAACCGCTTCGTTACGCTGGAAATGAAATATGGCCGGATCATGCTGGATACGGCCAAAATT
ATTGATGAGCAGGACGTTCCGACACATATCCTGAGCAAACTGACTTTTACTTTACGTAATCATCCTGAGTACCTAGAAGC
CTCTGTTTTGTCTCCCGATGATGTACGCCAAGTCCTGTCAATGGATTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References