Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2627647..2628175 Replicon chromosome
Accession NZ_CP082909
Organism Endozoicomonas sp. 4G

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K7B67_RS10395 Protein ID WP_252180263.1
Coordinates 2627647..2627937 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K7B67_RS10400 Protein ID WP_252180264.1
Coordinates 2627927..2628175 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7B67_RS10365 2623268..2623975 - 708 WP_252180258.1 AAA family ATPase -
K7B67_RS10370 2624113..2624769 + 657 WP_252177782.1 hypothetical protein -
K7B67_RS10375 2624655..2625479 + 825 WP_252180259.1 transposase -
K7B67_RS10380 2625486..2626721 + 1236 WP_252180260.1 ISAzo13 family transposase -
K7B67_RS10385 2626891..2627112 - 222 WP_252180261.1 ATP-binding protein -
K7B67_RS10390 2627203..2627457 + 255 WP_252180262.1 hypothetical protein -
K7B67_RS10395 2627647..2627937 - 291 WP_252180263.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K7B67_RS10400 2627927..2628175 - 249 WP_252180264.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
K7B67_RS10405 2628418..2629524 - 1107 WP_252180265.1 RNA-guided endonuclease TnpB family protein -
K7B67_RS10410 2629711..2630001 + 291 WP_252180266.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
K7B67_RS10415 2630077..2630382 - 306 WP_252180267.1 hypothetical protein -
K7B67_RS10420 2630872..2631651 + 780 WP_252180268.1 ABC transporter permease -
K7B67_RS10425 2631648..2632301 + 654 WP_252180269.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-74)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11204.23 Da        Isoelectric Point: 10.7635

>T215542 WP_252180263.1 NZ_CP082909:c2627937-2627647 [Endozoicomonas sp. 4G]
MSYELEFKKSALKEWKKLNPAVRDQFKKVLERRLVDPHVPSAQVSGAPNMYKIKLRQLGYRLIYSVSEKTITVRVLAIGK
RDKNEVYQVALSRLLQ

Download         Length: 291 bp

>T215542 NZ_CP110814:974788-975123 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8995.36 Da        Isoelectric Point: 4.0333

>AT215542 WP_252180264.1 NZ_CP082909:c2628175-2627927 [Endozoicomonas sp. 4G]
MASQILTDTAASISELKANPMKVVASGEGLPVAVLNRNEPAFYCVPAKAYEAMMELIEDLELLEIVKQRENEESVKVSLD
EL

Download         Length: 249 bp

>AT215542 NZ_CP110814:974540-974788 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References