Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prpT-prpA/ParE-CC2985
Location 2539531..2540081 Replicon chromosome
Accession NZ_CP082909
Organism Endozoicomonas sp. 4G

Toxin (Protein)


Gene name PrpT Uniprot ID -
Locus tag K7B67_RS09845 Protein ID WP_256484819.1
Coordinates 2539531..2539833 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PrpA Uniprot ID -
Locus tag K7B67_RS09850 Protein ID WP_252180163.1
Coordinates 2539839..2540081 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7B67_RS09835 2534787..2536706 + 1920 WP_252180160.1 TrbC family F-type conjugative pilus assembly protein -
K7B67_RS09840 2536703..2539513 + 2811 WP_252180161.1 conjugal transfer protein TraN -
K7B67_RS09845 2539531..2539833 - 303 WP_256484819.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K7B67_RS09850 2539839..2540081 - 243 WP_252180163.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
K7B67_RS09855 2540143..2540424 + 282 WP_252180164.1 type IV conjugative transfer system protein TraL -
K7B67_RS09860 2540521..2540892 + 372 WP_252180165.1 winged helix-turn-helix domain-containing protein -
K7B67_RS09865 2541317..2542282 + 966 WP_252180166.1 helix-turn-helix transcriptional regulator -
K7B67_RS09870 2542409..2542981 - 573 WP_252180167.1 PIN domain-containing protein -
K7B67_RS09875 2542981..2543439 - 459 WP_252180168.1 helix-turn-helix domain-containing protein -
K7B67_RS09880 2543481..2543741 - 261 WP_252180169.1 hypothetical protein -
K7B67_RS09885 2543834..2544388 + 555 WP_252180170.1 type IV conjugative transfer system protein TraE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2428018..2550960 122942


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-95)

Antitoxin

Antitoxin ParD

(5-74)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11959.64 Da        Isoelectric Point: 9.2190

>T215540 WP_256484819.1 NZ_CP082909:c2539833-2539531 [Endozoicomonas sp. 4G]
MPPNKQYLFKPRAQQDLEDIYDYSASEFGEEQADLYIRNLFDTFQRLAETPGFARYRDDIRKGLKSYPVKAHIVFFRKME
NGVLIVRVLHQSMDFQSKKY

Download         Length: 303 bp

>T215540 NZ_CP110814:717335-717631 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8914.05 Da        Isoelectric Point: 4.7863

>AT215540 WP_252180163.1 NZ_CP082909:c2540081-2539839 [Endozoicomonas sp. 4G]
MARTLTISLGDELQGYAQQLVDSGAYSSVSEVVREALRNLREQKASSNLEQLRAMIDEGDNSGEPVDLKVEKFLAQMKKR

Download         Length: 243 bp

>AT215540 NZ_CP110814:717633-718028 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References