Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2270997..2271541 Replicon chromosome
Accession NZ_CP082909
Organism Endozoicomonas sp. 4G

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K7B67_RS08810 Protein ID WP_252179978.1
Coordinates 2270997..2271272 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K7B67_RS08815 Protein ID WP_252179979.1
Coordinates 2271272..2271541 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7B67_RS08790 2266294..2267100 - 807 WP_252179974.1 TatD family hydrolase -
K7B67_RS08795 2267273..2268520 - 1248 WP_252179975.1 hypothetical protein -
K7B67_RS08800 2268645..2269208 + 564 WP_252179976.1 hypothetical protein -
K7B67_RS08805 2269346..2269594 + 249 WP_252179977.1 hypothetical protein -
K7B67_RS08810 2270997..2271272 - 276 WP_252179978.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K7B67_RS08815 2271272..2271541 - 270 WP_252179979.1 ribbon-helix-helix domain-containing protein Antitoxin
K7B67_RS08820 2271663..2271776 + 114 Protein_1745 helix-turn-helix domain-containing protein -
K7B67_RS08825 2271788..2272066 - 279 WP_252179980.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
K7B67_RS08830 2272292..2273107 + 816 WP_252179981.1 MOSC domain-containing protein -
K7B67_RS08835 2273212..2273715 - 504 WP_252179982.1 DUF29 domain-containing protein -
K7B67_RS08840 2273858..2274172 - 315 WP_252179983.1 type II toxin-antitoxin system RelE/ParE family toxin -
K7B67_RS08845 2274172..2274432 - 261 WP_252179984.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
K7B67_RS08850 2274550..2275368 - 819 WP_252179985.1 exodeoxyribonuclease III -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10737.30 Da        Isoelectric Point: 8.4942

>T215537 WP_252179978.1 NZ_CP082909:c2271272-2270997 [Endozoicomonas sp. 4G]
MEINWTSKALSDLSRLYDFLALVNKQAAAKTVQSLTSGPAILLENPRLGERVEAFDPREVRRVLIGQYEMRYEIQHSTIY
ILRFWHTREER

Download         Length: 276 bp

>T215537 NZ_CP110814:183756-183863 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10054.29 Da        Isoelectric Point: 4.5201

>AT215537 WP_252179979.1 NZ_CP082909:c2271541-2271272 [Endozoicomonas sp. 4G]
MAQTDTKVLTAHVPLSLAEKVEQLAQRLERSRGWIIKQALSAWIDQEEERDRLTREALADVDANAVIDHQAVQEWAESLG
TENPLPVPR

Download         Length: 270 bp

>AT215537 NZ_CP110814:c183707-183641 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References