Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 1682286..1683105 | Replicon | chromosome |
Accession | NZ_CP082909 | ||
Organism | Endozoicomonas sp. 4G |
Toxin (Protein)
Gene name | hepT | Uniprot ID | - |
Locus tag | K7B67_RS06550 | Protein ID | WP_252179553.1 |
Coordinates | 1682683..1683105 (+) | Length | 141 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | - |
Locus tag | K7B67_RS06545 | Protein ID | WP_252179552.1 |
Coordinates | 1682286..1682690 (+) | Length | 135 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
K7B67_RS06535 | 1677631..1678947 | + | 1317 | WP_252179550.1 | bifunctional tetrahydrofolate synthase/dihydrofolate synthase | - |
K7B67_RS06540 | 1679251..1682112 | + | 2862 | WP_252179551.1 | ankyrin repeat domain-containing protein | - |
K7B67_RS06545 | 1682286..1682690 | + | 405 | WP_252179552.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
K7B67_RS06550 | 1682683..1683105 | + | 423 | WP_252179553.1 | DUF86 domain-containing protein | Toxin |
K7B67_RS06555 | 1683293..1683616 | + | 324 | WP_252179554.1 | nucleotidyltransferase domain-containing protein | - |
K7B67_RS06560 | 1683620..1684126 | + | 507 | WP_252179555.1 | hypothetical protein | - |
K7B67_RS06565 | 1684119..1684550 | + | 432 | WP_252179556.1 | nucleotidyltransferase substrate binding protein | - |
K7B67_RS06570 | 1684658..1685083 | + | 426 | WP_252179557.1 | hypothetical protein | - |
K7B67_RS06575 | 1685279..1686751 | + | 1473 | WP_252179558.1 | lipid II flippase MurJ | - |
K7B67_RS06580 | 1686744..1687577 | + | 834 | WP_252179560.1 | aldolase/citrate lyase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 141 a.a. Molecular weight: 16125.57 Da Isoelectric Point: 6.8529
>T215536 WP_252179553.1 NZ_CP082909:1682683-1683105 [Endozoicomonas sp. 4G]
MNDIILNKYSIIQRCIARINEEYKGHESELCTNYTQQDSIILNIQRACQAAQDMANYVIKLKKLGIPQNARESFQLLNDH
GLVSAPLTISMIKMVGFRNIAVHEYQKLNIAILKSVIEKHVDEINWFAEEVMRSFNNDGQ
MNDIILNKYSIIQRCIARINEEYKGHESELCTNYTQQDSIILNIQRACQAAQDMANYVIKLKKLGIPQNARESFQLLNDH
GLVSAPLTISMIKMVGFRNIAVHEYQKLNIAILKSVIEKHVDEINWFAEEVMRSFNNDGQ
Download Length: 423 bp
>T215536 NZ_CP110812:c2221953-2221603 [Bacillus paralicheniformis]
TTGATTGTTAAACGCGGCGATGTTTATTTTGCTGACCTATCTCCTGTTGTTGGCTCAGAACAAGGCGGGGTGCGCCCGGT
TTTAGTGATTCAAAACAACATCGGCAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CAAAATTACCTACCCACGTCGAAATTGATGCGAAACGCTACGGTTTTGAAAGAGATTCCGTTATATTGCTCGAACAAATT
CGGACGATTGACAAGCAAAGATTAACGGACAAAATCACTCATCTCGATGATGAAATGATGGAAAAGGTCAACGAAGCCTT
ACAAATCAGTTTGGCACTCATTGATTTTTAA
TTGATTGTTAAACGCGGCGATGTTTATTTTGCTGACCTATCTCCTGTTGTTGGCTCAGAACAAGGCGGGGTGCGCCCGGT
TTTAGTGATTCAAAACAACATCGGCAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CAAAATTACCTACCCACGTCGAAATTGATGCGAAACGCTACGGTTTTGAAAGAGATTCCGTTATATTGCTCGAACAAATT
CGGACGATTGACAAGCAAAGATTAACGGACAAAATCACTCATCTCGATGATGAAATGATGGAAAAGGTCAACGAAGCCTT
ACAAATCAGTTTGGCACTCATTGATTTTTAA
Antitoxin
Download Length: 135 a.a. Molecular weight: 15302.36 Da Isoelectric Point: 4.3377
>AT215536 WP_252179552.1 NZ_CP082909:1682286-1682690 [Endozoicomonas sp. 4G]
MEPLHKAVIISFLRRAYGDLLQGILLFGSHANGTANKESDIDLGILIDGMADPVELWENAQTLASQVNTNIDLVDLRAAT
TVLQHEVINTGIWLWQQDTVTCDLFELQVMSLYQQLQYDRREILNDLQRRLHNE
MEPLHKAVIISFLRRAYGDLLQGILLFGSHANGTANKESDIDLGILIDGMADPVELWENAQTLASQVNTNIDLVDLRAAT
TVLQHEVINTGIWLWQQDTVTCDLFELQVMSLYQQLQYDRREILNDLQRRLHNE
Download Length: 405 bp
>AT215536 NZ_CP110812:c2222239-2221958 [Bacillus paralicheniformis]
TTGTCTGAATCCAGCGCTACAACTGAAATATTGATTCGCTTGCCAGAAGCTTTAGTATCAGAACTGGATGGTGTCGTCAT
GCAAGATAACGGGAGCAGAAATGAACTGATTTACCAAGCCACAAAAATGTATTTGCGCGAGCGCAAAAATCGACAAATTC
GGGAATCGATGAGACGCGGTTATATGGAGATGGCCAAGATTAATTTGAACATCTCTTCTGAGGCTCAATTTGCAGAGTAT
GAGGCTGAAAACACAGTAGAGCGCTTAGTAAGCGGAGGATAA
TTGTCTGAATCCAGCGCTACAACTGAAATATTGATTCGCTTGCCAGAAGCTTTAGTATCAGAACTGGATGGTGTCGTCAT
GCAAGATAACGGGAGCAGAAATGAACTGATTTACCAAGCCACAAAAATGTATTTGCGCGAGCGCAAAAATCGACAAATTC
GGGAATCGATGAGACGCGGTTATATGGAGATGGCCAAGATTAATTTGAACATCTCTTCTGAGGCTCAATTTGCAGAGTAT
GAGGCTGAAAACACAGTAGAGCGCTTAGTAAGCGGAGGATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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