Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 1682286..1683105 Replicon chromosome
Accession NZ_CP082909
Organism Endozoicomonas sp. 4G

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag K7B67_RS06550 Protein ID WP_252179553.1
Coordinates 1682683..1683105 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag K7B67_RS06545 Protein ID WP_252179552.1
Coordinates 1682286..1682690 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7B67_RS06535 1677631..1678947 + 1317 WP_252179550.1 bifunctional tetrahydrofolate synthase/dihydrofolate synthase -
K7B67_RS06540 1679251..1682112 + 2862 WP_252179551.1 ankyrin repeat domain-containing protein -
K7B67_RS06545 1682286..1682690 + 405 WP_252179552.1 nucleotidyltransferase domain-containing protein Antitoxin
K7B67_RS06550 1682683..1683105 + 423 WP_252179553.1 DUF86 domain-containing protein Toxin
K7B67_RS06555 1683293..1683616 + 324 WP_252179554.1 nucleotidyltransferase domain-containing protein -
K7B67_RS06560 1683620..1684126 + 507 WP_252179555.1 hypothetical protein -
K7B67_RS06565 1684119..1684550 + 432 WP_252179556.1 nucleotidyltransferase substrate binding protein -
K7B67_RS06570 1684658..1685083 + 426 WP_252179557.1 hypothetical protein -
K7B67_RS06575 1685279..1686751 + 1473 WP_252179558.1 lipid II flippase MurJ -
K7B67_RS06580 1686744..1687577 + 834 WP_252179560.1 aldolase/citrate lyase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(21-98)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16125.57 Da        Isoelectric Point: 6.8529

>T215536 WP_252179553.1 NZ_CP082909:1682683-1683105 [Endozoicomonas sp. 4G]
MNDIILNKYSIIQRCIARINEEYKGHESELCTNYTQQDSIILNIQRACQAAQDMANYVIKLKKLGIPQNARESFQLLNDH
GLVSAPLTISMIKMVGFRNIAVHEYQKLNIAILKSVIEKHVDEINWFAEEVMRSFNNDGQ

Download         Length: 423 bp

>T215536 NZ_CP110812:c2221953-2221603 [Bacillus paralicheniformis]
TTGATTGTTAAACGCGGCGATGTTTATTTTGCTGACCTATCTCCTGTTGTTGGCTCAGAACAAGGCGGGGTGCGCCCGGT
TTTAGTGATTCAAAACAACATCGGCAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CAAAATTACCTACCCACGTCGAAATTGATGCGAAACGCTACGGTTTTGAAAGAGATTCCGTTATATTGCTCGAACAAATT
CGGACGATTGACAAGCAAAGATTAACGGACAAAATCACTCATCTCGATGATGAAATGATGGAAAAGGTCAACGAAGCCTT
ACAAATCAGTTTGGCACTCATTGATTTTTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15302.36 Da        Isoelectric Point: 4.3377

>AT215536 WP_252179552.1 NZ_CP082909:1682286-1682690 [Endozoicomonas sp. 4G]
MEPLHKAVIISFLRRAYGDLLQGILLFGSHANGTANKESDIDLGILIDGMADPVELWENAQTLASQVNTNIDLVDLRAAT
TVLQHEVINTGIWLWQQDTVTCDLFELQVMSLYQQLQYDRREILNDLQRRLHNE

Download         Length: 405 bp

>AT215536 NZ_CP110812:c2222239-2221958 [Bacillus paralicheniformis]
TTGTCTGAATCCAGCGCTACAACTGAAATATTGATTCGCTTGCCAGAAGCTTTAGTATCAGAACTGGATGGTGTCGTCAT
GCAAGATAACGGGAGCAGAAATGAACTGATTTACCAAGCCACAAAAATGTATTTGCGCGAGCGCAAAAATCGACAAATTC
GGGAATCGATGAGACGCGGTTATATGGAGATGGCCAAGATTAATTTGAACATCTCTTCTGAGGCTCAATTTGCAGAGTAT
GAGGCTGAAAACACAGTAGAGCGCTTAGTAAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References