Detailed information of TA system TA215534

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 1587749..1588287
• Replicon: chromosome
• Accession: NZ_CP082909
• Organism: Endozoicomonas sp. 4G

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: K7B67_RS06015
• Protein ID: WP_252179454.1
• Coordinates: 1587749..1588048 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: K7B67_RS06020
• Protein ID: WP_252179455.1
• Coordinates: 1588045..1588287 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K7B67_RS05985	1582939..1583517	+	579	WP_252179448.1	hypothetical protein	-
K7B67_RS05990	1583514..1583816	+	303	WP_252179449.1	hypothetical protein	-
K7B67_RS05995	1583975..1585114	+	1140	WP_252179450.1	ISAs1 family transposase	-
K7B67_RS06000	1585484..1585699	+	216	WP_252179451.1	DUF6500 family protein	-
K7B67_RS06005	1585831..1586862	+	1032	WP_252179452.1	hypothetical protein	-
K7B67_RS06010	1586978..1587682	+	705	WP_252179453.1	aspartate/glutamate racemase family protein	-
K7B67_RS06015	1587749..1588048	-	300	WP_252179454.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
K7B67_RS06020	1588045..1588287	-	243	WP_252179455.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
K7B67_RS06025	1588536..1588907	+	372	Protein_1196	VOC family protein	-
K7B67_RS06030	1589037..1589456	+	420	WP_252179456.1	GFA family protein	-
K7B67_RS06035	1589545..1590087	+	543	WP_252179457.1	DinB family protein	-
K7B67_RS06040	1590281..1590565	+	285	WP_252179458.1	hypothetical protein	-
K7B67_RS06045	1590682..1591449	+	768	WP_252179459.1	AAA family ATPase	-
K7B67_RS06050	1591993..1592163	+	171	WP_252179460.1	hypothetical protein	-
K7B67_RS06055	1592559..1593065	-	507	WP_252179461.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1583514..1628818	45304
	-	inside	Integron	-	-	1585484..1591449	5965

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-92)

Antitoxin

• Antitoxin ParD (1-78)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11853.89 Da
• Isoelectric Point: 10.6247

>T215534 WP_252179454.1 NZ_CP082909:c1588048-1587749 [Endozoicomonas sp. 4G]
MKPFILTQKAKADLKEIAKFTMKRWGREKRNLYLKEFDQAFFFLAERPSIGKSCDEIRKGYRKFPQGSHIIFYKQNDKNQ
INIIRLLHKSMDVDIHFSA

Nucleotide

• Length: 300 bp

>T215534 NZ_CP110811:c21937-21611 [Pseudomonas syringae]
ATGATGCGAGGTGACCTAGTCACCGTCGCCATGCAAGGTGACTTTGGTAAACCAAGACCCGCCTTGGTAATTCAGGCAAA
CCAATTCAGCGAACACACCAGCGTTACCGTGCTGCCAGTGACCAGCACCCTAGTCGCAGCACCGCTGCTGCGCATCACCG
TTCAGCCGACCGCAGAAAACGGCTTGCAGAAGCCTTCTCAGGTCATGCTAGACAAGACCATGACACTCAAGCGTGAAAAA
ATAGGTCCGACTTTTGGGCATATCGGAGTGGATTCAATGGTGGAGGTGGAGCGCTGTTTAGCCGTGTTCTTGGGTATCGC
CAATTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9105.09 Da
• Isoelectric Point: 4.3566

>AT215534 WP_252179455.1 NZ_CP082909:c1588287-1588045 [Endozoicomonas sp. 4G]
MGKNTSITLGEHFDWFISNQVKSGRYGSASEVIRAALRLLESKETKINTLRNLLIEGEESGMAEYDYDTFINELDDETNK

Nucleotide

• Length: 243 bp

>AT215534 NZ_CP110811:c22158-21934 [Pseudomonas syringae]
ATGCCTACATCCCATGTAAATGCCCGCGTTCAACGCCATCGCGACGCGCTGCGTGCGGCTGGCCTACGGCCCATTCAGAT
TTGGGTTCCCGATACCCGGCGGCCAGACTTTGCACAGGAGTGCCATCGACAGTGCCTGTTGGTTGCTCAGGCAGACATGG
CCAATACCTATATGCAGGGGTTGATGGACGAAGCCTTAGACGATGTTGAGGGTTGGACGCCATGA