Detailed information of TA system TA215533

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 1295738..1296300
• Replicon: chromosome
• Accession: NZ_CP082909
• Organism: Endozoicomonas sp. 4G

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: K7B67_RS04810
• Protein ID: WP_252179233.1
• Coordinates: 1295738..1296016 (-)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: K7B67_RS04815
• Protein ID: WP_252179234.1
• Coordinates: 1296016..1296300 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K7B67_RS04760	1291568..1292056	+	489	WP_252179224.1	DUF29 domain-containing protein	-
K7B67_RS04765	1292387..1292716	+	330	WP_252179225.1	helix-turn-helix transcriptional regulator	-
K7B67_RS04770	1292870..1293103	+	234	WP_252179226.1	ParD-like family protein	-
K7B67_RS04775	1293100..1293384	+	285	WP_252179227.1	type II toxin-antitoxin system RelE/ParE family toxin	-
K7B67_RS04780	1293487..1293585	+	99	Protein_950	transposase	-
K7B67_RS04785	1293672..1294178	+	507	WP_252179228.1	DUF29 domain-containing protein	-
K7B67_RS04790	1294235..1294567	-	333	WP_252179229.1	type II toxin-antitoxin system HicB family antitoxin	-
K7B67_RS04795	1294564..1294818	-	255	WP_252179230.1	type II toxin-antitoxin system HicA family toxin	-
K7B67_RS04800	1295012..1295278	+	267	WP_252179231.1	hypothetical protein	-
K7B67_RS04805	1295265..1295639	+	375	WP_252179232.1	hypothetical protein	-
K7B67_RS04810	1295738..1296016	-	279	WP_252179233.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
K7B67_RS04815	1296016..1296300	-	285	WP_252179234.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
K7B67_RS04820	1296579..1297412	+	834	WP_252179235.1	hypothetical protein	-
K7B67_RS04825	1297490..1298239	+	750	WP_252179236.1	HIRAN domain-containing protein	-
K7B67_RS04830	1298564..1298851	+	288	WP_252179237.1	BrnA antitoxin family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1290884..1291273	389

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-44)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 11009.71 Da
• Isoelectric Point: 4.5702

>T215533 WP_252179233.1 NZ_CP082909:c1296016-1295738 [Endozoicomonas sp. 4G]
MIYWEVESLNDREKIFEFIYEFNPIAAEKTDEVIEAKVENLLEQPYMGVERDGIRGRLLIIPEVSMIVSYYIDNKNIRVM
RVLHQKQKFPTD

Nucleotide

• Length: 279 bp

>T215533 NZ_CP110811:c20449-20177 [Pseudomonas syringae]
GTGCTAGTTGAGTGGCTTCCACAAGCTTTGGAGGCACTGGAGGAAATCGCCGGCTACCTAGCCGAGCGCAACCCTTATGC
TGCCGAGCAGATGCAGGCCACCCTTGAGGCCACGGTCGAGGCTCTCCCCCTGCACCCTTACATCCACCGTCCCGGCCGTG
TTCCAGGAACGCGCGAAGCGGTTGTGCATCCCAACTACCTGGTTGTCTACCGCGTCGGTACAGAGCGCATCAGCATCTTG
GACGTCCTGCACGCCCGCCAAGAGTACCCCTAG

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 11180.67 Da
• Isoelectric Point: 9.7486

>AT215533 WP_252179234.1 NZ_CP082909:c1296300-1296016 [Endozoicomonas sp. 4G]
METRIQFRVDEETKRLAQQMTESQGRTISDACRELTEQLADQQRKILSQEAWLTEQVNLAFEKLDSHKSNFIEHDAAKNE
MIKRKAKIRKRGYR

Nucleotide

• Length: 285 bp

>AT215533 NZ_CP110811:c20624-20439 [Pseudomonas syringae]
ATGAGCATTCAACTTGACCCTCGCGTCTCGGAGTTCGAGACCCAGGAACAGGCCGACAATTACGACCGTTGGTTTCGCCA
GCGTATCGAGCACAGTTTGGCCGATCCGCGTCCACCCGTGCCGCACGATGAAGCAATGGCTCGCGTCAGAGCCATGATCG
AAGCAAAGCGCCGCCGTGCTAGTTGA