Detailed information of TA system TA215532

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mosAT/AbiEii-AbiEi
• Location: 1161381..1163117
• Replicon: chromosome
• Accession: NZ_CP082909
• Organism: Endozoicomonas sp. 4G

Toxin (Protein)

• Gene name: mosT
• Uniprot ID: -
• Locus tag: K7B67_RS04340
• Protein ID: WP_252179147.1
• Coordinates: 1162176..1163117 (+)
• Length: 314 a.a.

Antitoxin (Protein)

• Gene name: mosA
• Uniprot ID: -
• Locus tag: K7B67_RS04335
• Protein ID: WP_252179146.1
• Coordinates: 1161381..1162148 (+)
• Length: 256 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K7B67_RS04310	1157143..1157610	-	468	WP_252179141.1	hypothetical protein	-
K7B67_RS04315	1157957..1158406	-	450	WP_252179142.1	YcgN family cysteine cluster protein	-
K7B67_RS04320	1158403..1158699	-	297	WP_252179143.1	YcgL domain-containing protein	-
K7B67_RS04325	1158760..1159905	-	1146	WP_252179144.1	ribonuclease D	-
K7B67_RS04330	1160044..1160931	-	888	WP_252179145.1	protease HtpX	-
K7B67_RS04335	1161381..1162148	+	768	WP_252179146.1	type IV toxin-antitoxin system AbiEi family antitoxin	Antitoxin
K7B67_RS04340	1162176..1163117	+	942	WP_252179147.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
K7B67_RS04345	1163188..1163652	-	465	WP_252179148.1	hypothetical protein	-
K7B67_RS04350	1163652..1164866	-	1215	WP_252179149.1	pyridoxal phosphate-dependent aminotransferase	-
K7B67_RS04355	1165138..1165530	+	393	WP_252179150.1	peptide-methionine (R)-S-oxide reductase MsrB	-
K7B67_RS04360	1165559..1167913	-	2355	WP_252179151.1	response regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (14-265)

Antitoxin

• Transcriptional regulator AbiEi antitoxin, N-terminal domain (1-98)

Sequences

Toxin

Protein

• Length: 314 a.a.
• Molecular weight: 35994.26 Da
• Isoelectric Point: 5.6922

>T215532 WP_252179147.1 NZ_CP082909:1162176-1163117 [Endozoicomonas sp. 4G]
MDKTSAYYRQVSLLIRMLPVVAIEPVFALKGGTAINLFVQDFPRLSVDIDLAYLPLEPRDEALQNVRSALERIAERINTQ
PSTRAVLQGNRQDELRIIVTTESATIKIEVSPVARGTLHDPELLPVVESVEEEFGYTEIPVVSQADLYGGKLCAAMDRQH
PRDLYDVQQLLNAGGISREIFTGFLTYTLSHPRPIHEVMSPRWKELEQTFYDEFVGMTNEPVELNELIETRSRMVAALQA
RFTKRDHDFLLSFKQGKPNWALFDEPSAAKLPAIRWKLMNIQRLSKNRDKHQQQLEKLENTLEHWLLMTENRI

Nucleotide

• Length: 942 bp

>T215532 NZ_CP110811:13256-13606 [Pseudomonas syringae]
ATGAATACGTTTGCACTACGCTTTACCGAGGTTGCCCAGCAAAGCCTCGAAGATCAGGTTGAACATCTGGCTGTCTATCA
GGGATTCTCATCAGCTGCTCAACGCATAGATTCCCTTATCGATGCCATCCAGGACAAGCTCCTGTCCACCCCGTTGGGCT
ACCCGGTCAGTCCACAGTTGAGTGAGCTGGGTGTACTGCACTATCGTGAGTTGAACACTGACGGATACCGGATCTTTTAT
GAGGTGATGGATTCTGATGGTATTAACGACATCGCCGTATTGCTCGTATTGGGTGGTAAACAGAGTGTTGAACAGGCACT
GATCCGCTACTGTCTGCTACAGCCTATGTAG

Antitoxin

Protein

• Length: 256 a.a.
• Molecular weight: 29274.34 Da
• Isoelectric Point: 10.0525

>AT215532 WP_252179146.1 NZ_CP082909:1161381-1162148 [Endozoicomonas sp. 4G]
MSSKINWLINHTSPGSLVLQQWLTENGIRYSLAQKYTQSGWLKRLSPGVYYRPEPSSGKIKPEWPDAIQALTQQLQLPVH
LAGLSSLTHQGLSHYLQLNSEQVWVGTRSKQALPKWFREFSERPWLYSGNHKLGELNDKDFTTVTVKRKELRASCPELAA
YEVVDAIGKNIRFEHAAELFQGLVNLSPRKVQSLLNRSSAVKTNRIFLFLSHYCDHQWFGRLDESQIQLGSGKRQVVING
RYDERYQITVPQSLP

Nucleotide

• Length: 768 bp

>AT215532 NZ_CP110811:12995-13243 [Pseudomonas syringae]
ATGCGAGTTGAAACAATAAGTTATCTGAAACGCAACGCAGCCGACCTGCCTCTCGATGAGCCATTGGTCGTCACGCAAAA
CGGTGTCCCGGCCTACGTGGTGGAGTCTTACGCTGATCGTAAGCGCCGCGATGAGTCAATTGCCTTGGTGAAGCTCCTGG
CAATCAGCTCCCGCGAGTACTCCCAAGGCAAGCACTGTTCCACTGACGAACTCAAAGCCCGATTGAGCAGGAGGTTTGCC
CAAAAATAA